Liquid biopsies to occult brain metastasis

AU Rehman, P Khan, SK Maurya, JA Siddiqui… - Molecular cancer, 2022 - Springer
Brain metastasis (BrM) is a major problem associated with cancer-related mortality, and
currently, no specific biomarkers are available in clinical settings for early detection. Liquid …

The role of liquid biopsies in detecting molecular tumor biomarkers in brain cancer patients

H Sareen, C Garrett, D Lynch, B Powter, D Brungs… - Cancers, 2020 - mdpi.com
Glioblastoma multiforme (GBM) is one of the most lethal primary central nervous system
cancers with a median overall survival of only 12–15 months. The best documented …

Adding value to liquid biopsy for brain tumors: The role of imaging

N Khalili, H Shooli, N Hosseini, A Fathi Kazerooni… - Cancers, 2023 - mdpi.com
Simple Summary Clinical management in neuro-oncology has shifted to an integrated
method that combines molecular profiles with histopathological and imaging data. Liquid …

Liquid biopsy and primary brain tumors

RH Eibl, M Schneemann - Cancers, 2021 - mdpi.com
Simple Summary Despite a substantial increase in publications in recent years, liquid biopsy
from blood, cerebrospinal fluid (CSF), and other body fluids is usually not routinely used in …

Recent advances in liquid biopsy of brain cancers

Y An, F Fan, X Jiang, K Sun - Frontiers in Genetics, 2021 - frontiersin.org
Brain cancers are among the top causes of death worldwide. Although, the survival rates
vary widely depending on the type of the tumor, early diagnosis could generally benefit in …

Liquid biopsy: creating opportunities in brain space

R Trivedi, KP Bhat - British journal of cancer, 2023 - nature.com
In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications

A Boire, D Brandsma, PK Brastianos… - Neuro …, 2019 - academic.oup.com
Liquid biopsies collect and analyze tumor components in body fluids, and there is an
increasing interest in the investigation of liquid biopsies as a surrogate for tumor tissue in the …

[HTML][HTML] Cerebrospinal fluid biomarkers for brain tumor detection: clinical roles and current progress

F Xiao, S Lv, Z Zong, L Wu, X Tang… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Brain tumors include those that originate within the brain (primary tumors) as well as those
that arise from other cancers (metastatic tumors). The fragile nature of the brain poses a …

Peering through a keyhole: liquid biopsy in primary and metastatic central nervous system tumours

L Bertero, G Siravegna, R Rudà… - Neuropathology and …, 2019 - Wiley Online Library
Tumour molecular profiling by liquid biopsy is being investigated for a wide range of
research and clinical purposes. The possibility of repeatedly interrogating the tumour profile …

The double agents in liquid biopsy: promoter and informant biomarkers of early metastases in breast cancer

V Richard, MG Davey, H Annuk, N Miller, MJ Kerin - Molecular Cancer, 2022 - Springer
Breast cancer continues to be a major global problem with significant mortality associated
with advanced stage and metastases at clinical presentation. However, several findings …