Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects multiple
brain regions and is difficult to treat. In this study we used 22 AD large-scale gene …

Alzheimer's disease (AD) is a complex and heterogenous brain disease that affects multiple
inter-related biological processes. This complexity contributes, in part, to existing difficulties …

Abstract Background Transcriptional studies suggest Alzheimer's disease (AD) involves
dysfunction of many cellular pathways, including synaptic transmission, cytoskeletal …

Alzheimer's disease (AD) is one of the most common neurodegeneration diseases caused
by multiple factors. The mechanistic insight of AD remains limited. To disclose molecular …

Background: The pathogenesis of Alzheimer's disease (AD) remains to be elucidated. This
study aimed to identify the hub genes in AD pathogenesis and determine their functions and …

Alzheimer's disease (AD) affects a significant portion of elderly people worldwide. Although
the amyloid-β (Aβ) cascade hypothesis has been the prevailing theory for the molecular …

To generate new insights into the biology of Alzheimer's Disease (AD), we developed
methods to combine and reuse a wide variety of existing data sets in new ways. We first …

Motivation Alzheimer's disease (AD) is a serious degenerative brain disease and the most
common cause of dementia. The current available drugs for AD provide symptomatic benefit …

Background Our understanding of the molecular mechanisms underlying Alzheimer's
disease (AD) remains incomplete. Previous studies have revealed that genetic factors …

End-stage Alzheimer's disease (AD) involves drastic modifications in neuronal molecular
and cellular processes, but little is known about the dynamics of these modifications during …