More than 100 distinct chemical modifications to RNA have been characterized so far.
However, the prevalence, mechanisms and functions of various RNA modifications remain …

Although more than 100 different types of RNA modifications have been characterized
across all living organisms, surprisingly little is known about the modified positions and their …

Although over 170 chemical modifications have been identified, their prevalence,
mechanism and function remain largely unknown. To enable integrated analysis of diverse …

The alphabet of building blocks for RNA molecules is much larger than the standard four
nucleotides. The diversity is achieved by the post-transcriptional biochemical modification of …

Dynamic and reversible RNA modifications such as N 6-methyladenosine (m6A) can play
important roles in regulating messenger RNA (mRNA) splicing, export, stability and …

Biological features, such as genes and transcription factor binding sites, are often denoted
with genome‐based coordinates as the genomic features. While genome‐based …

Deciphering the biological impacts of millions of single nucleotide variants remains a major
challenge. Recent studies suggest that RNA modifications play versatile roles in essential …

With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …

In the last decade, the notion that mRNA modifications are involved in regulation of gene
expression was demonstrated in thousands of studies. To date, new technologies and …

The precise mapping and quantification of the numerous RNA modifications that are present
in tRNAs, rRNAs, ncRNAs/miRNAs, and mRNAs remain a major challenge and a top priority …