Abstract Background Tumor-associated macrophages (TAMs) play a critical role in
modulating the tumor microenvironment and promote tumor metastases. Our studies have …

Abstract Ginsenoside Rh2 (Rh2), the major bio-active ginsenoside that originated from the
root of Panax ginseng, has become a “hot topic” for playing multifunctional roles in both …

Background Lung cancer has a high incidence worldwide, and most lung cancer-associated
deaths are attributable to cancer metastasis. Although several medicinal properties of Panax …

The epithelial-mesenchymal transition (EMT) is an important factor in lung cancer
metastasis, and targeting EMT is a potential therapeutic strategy. Fucosyltransferase IV …

Anti-angiogenic therapy has been successfully applied to treat colorectal cancer (CRC).
Ginsenoside Rg3, derived from the Chinese herb ginseng, has anti-vascularization effects …

Cisplatin is a first line chemotherapy in lung cancer, but decreased susceptibility may limit its
application. In solid tumors, hypoxia alters the microenvironment and is associated with …

The tumor microenvironment (TME) plays a key role in promoting the initiation and
progression of tumors, leading to chemoradiotherapy resistance and immunotherapy failure …

Accumulating evidence suggests that Ginsenoside Rg3 appears to inhibit tumor growth
including Lewis lung carcinoma, intestinal adenocarcinomas or B16 melanoma by inhibiting …

Background: Ginsenoside Rh2 (Rh2) is a major biological component of ginseng that exerts
antitumor activities in multiple cancers including Non-Small Cell Lung Cancers (NSCLCs) …

The epithelial–mesenchymal transition (EMT) is a pivotal cellular process during which
epithelial polarized cells become motile mesenchymal-appearing cells, which, in turn …