Fornix integrity and hippocampal volume predict memory decline and progression to Alzheimer's disease
BACKGROUND: The fornix is the predominant outflow tract of the hippocampus, a brain
region known to be affected early in the course of Alzheimer's disease (AD). The aims of the …
region known to be affected early in the course of Alzheimer's disease (AD). The aims of the …
[HTML][HTML] Sub-regional hippocampal injury is associated with fornix degeneration in Alzheimer's disease
DY Lee, E Fletcher, OT Carmichael, B Singh… - Frontiers in aging …, 2012 - frontiersin.org
We examined in vivo evidence of axonal degeneration in association with neuronal
pathology in Alzheimer's disease (AD) through analysis of fornix microstructural integrity and …
pathology in Alzheimer's disease (AD) through analysis of fornix microstructural integrity and …
Loss of fornix white matter volume as a predictor of cognitive impairment in cognitively normal elderly individuals
E Fletcher, M Raman, P Huebner, A Liu… - JAMA …, 2013 - jamanetwork.com
Importance Magnetic resonance imaging markers of incipient cognitive decline among
healthy elderly individuals have become important for both clarifying the biological …
healthy elderly individuals have become important for both clarifying the biological …
Hippocampal volume is related to cognitive decline and fornicial diffusion measures in multiple sclerosis
Purpose To assess for associations between hippocampal atrophy and measures of
cognitive function, hippocampal magnetization transfer ratio (MTR), and diffusion measures …
cognitive function, hippocampal magnetization transfer ratio (MTR), and diffusion measures …
[HTML][HTML] Fornix as an imaging marker for episodic memory deficits in healthy aging and in various neurological disorders
The fornix is a part of the limbic system and constitutes the major efferent and afferent white
matter tracts from the hippocampi. The underdevelopment of or injuries to the fornix are …
matter tracts from the hippocampi. The underdevelopment of or injuries to the fornix are …
[HTML][HTML] Alzheimer's disease and the fornix
K Oishi, CG Lyketsos - Frontiers in aging neuroscience, 2014 - frontiersin.org
Alzheimer's disease (AD) is the most common form of neurodegenerative dementia.
Researchers have long been focused on the cortical pathology of AD, since the most …
Researchers have long been focused on the cortical pathology of AD, since the most …
[HTML][HTML] Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease
CA Brown, NF Johnson, AJ Anderson-Mooney… - NeuroImage: Clinical, 2017 - Elsevier
We developed a merged younger-older adult template of the fornix and demonstrated its
utility for studies of aging and preclinical Alzheimer's disease (AD). In Experiment 1 …
utility for studies of aging and preclinical Alzheimer's disease (AD). In Experiment 1 …
The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease
The hippocampal complex, strongly implicated in Alzheimer's disease (AD), is a region with
functionally and structurally distinct subfields. Hippocampal subfield volumes may represent …
functionally and structurally distinct subfields. Hippocampal subfield volumes may represent …
[HTML][HTML] Fractional anisotropy of the fornix and hippocampal atrophy in Alzheimer's disease
K Kantarci - Frontiers in aging neuroscience, 2014 - frontiersin.org
Decrease in the directionality of water diffusion measured with fractional anisotropy (FA) on
diffusion tensor imaging has been linked to loss of myelin and axons in the white matter …
diffusion tensor imaging has been linked to loss of myelin and axons in the white matter …
[HTML][HTML] Cholinergic basal forebrain structure influences the reconfiguration of white matter connections to support residual memory in mild cognitive impairment
NJ Ray, C Metzler-Baddeley… - Journal of …, 2015 - Soc Neuroscience
The fornix and hippocampus are critical to recollection in the healthy human brain. Fornix
degeneration is a feature of aging and Alzheimer9s disease. In the presence of fornix …
degeneration is a feature of aging and Alzheimer9s disease. In the presence of fornix …