Ginsenoside Rh4 inhibits inflammation-related hepatocellular carcinoma progression by targeting HDAC4/IL-6/STAT3 signaling
R Jiang, S Luo, M Zhang, W Wang, S Zhuo… - Molecular Genetics and …, 2023 - Springer
This study aimed to investigate the effects of Ginsenoside Rh4 (Rh4) on inflammation-
related hepatocellular carcinoma (HCC) progression and the underlying mechanism. HCC …
related hepatocellular carcinoma (HCC) progression and the underlying mechanism. HCC …
Transcriptome analysis of the anti-proliferative effects of ginsenoside Rh3 on HCT116 colorectal cancer cells
S Teng, X Lei, X Zhang, D Shen, Q Liu, Y Sun, Y Wang… - Molecules, 2022 - mdpi.com
The mechanism of ginsenoside Rh3 activity against cancer remains unclear. This study
aimed to investigate the underlying mechanism. The effects of Rh3 on the cell proliferation …
aimed to investigate the underlying mechanism. The effects of Rh3 on the cell proliferation …
Ginsenoside Rk3 suppresses hepatocellular carcinoma development through targeting the gut-liver axis
L Qu, X Ma, D Fan - Journal of Agricultural and Food Chemistry, 2021 - ACS Publications
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. Our
previous reports showed that ginsenoside Rk3 provided excellent efficacy in alleviating the …
previous reports showed that ginsenoside Rk3 provided excellent efficacy in alleviating the …
Ginsenoside Rh2 and its octyl ester derivative inhibited invasion and metastasis of hepatocellular carcinoma via the c-Jun/COX2/PGE2 pathway
QR Hu, QX Huang, H Hong, Y Pan, T Luo, J Li… - Phytomedicine, 2023 - Elsevier
Abstracts Background Liver cancer is a topical global health issue. The treatment of liver
cancer meets significant challenges in the high recurrence rate and invasive incidence …
cancer meets significant challenges in the high recurrence rate and invasive incidence …
Ginsenoside Rh1 induces MCF-7 cell apoptosis and autophagic cell death through ROS-mediated Akt signaling
Simple Summary Breast cancer (BC) is the most common cause of cancer-related deaths
among women worldwide, and its incidence has been increasing. However, current …
among women worldwide, and its incidence has been increasing. However, current …
MicroRNA‑146a‑5p enhances ginsenoside Rh2‑induced anti‑proliferation and the apoptosis of the human liver cancer cell line HepG2
W Chen, S Chu, H Li, Y Qiu - Oncology Letters, 2018 - spandidos-publications.com
Liver cancer is one of the leading causes of malignancy‑associated mortality worldwide and
its clinical therapy remains very challenging. Ginsenoside Rh2 (Rh2) has been reported to …
its clinical therapy remains very challenging. Ginsenoside Rh2 (Rh2) has been reported to …
Minor ginsenoside Rg2 and Rh1 attenuates LPS-induced acute liver and kidney damages via downregulating activation of TLR4-STAT1 and inflammatory cytokine …
DTN Huynh, N Baek, S Sim, CS Myung… - International Journal of …, 2020 - mdpi.com
Ginsenosides have been reported to have various biological effects, such as immune
regulation and anticancer activity. In this study, we investigated the anti-inflammatory role of …
regulation and anticancer activity. In this study, we investigated the anti-inflammatory role of …
Ginsenoside Rh4 suppresses metastasis of Esophageal Cancer and expression of c-Myc via targeting the Wnt/β-Catenin signaling pathway
J Chen, Z Duan, Y Liu, R Fu, C Zhu - Nutrients, 2022 - mdpi.com
The metastasis of esophageal squamous cell carcinoma (ESCC) is a leading cause of death
worldwide, however, it has a poor prognosis. Ginsenoside Rh4 is a rare saponin that has …
worldwide, however, it has a poor prognosis. Ginsenoside Rh4 is a rare saponin that has …
Ginsenoside Rh1 suppresses matrix metalloproteinase-1 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathway …
JH Yoon, YJ Choi, SG Lee - European journal of pharmacology, 2012 - Elsevier
Invasion and metastasis are the major causes of treatment failure in patients with cancer.
Here, we investigated the effects of ginsenoside Rh1 on tumor invasion and metastasis in …
Here, we investigated the effects of ginsenoside Rh1 on tumor invasion and metastasis in …
Ginsenoside Rh2 induces apoptosis and inhibits epithelial-mesenchymal transition in HEC1A and Ishikawa endometrial cancer cells
JH Kim, M Kim, SM Yun, S Lee, JH No, DH Suh… - Biomedicine & …, 2017 - Elsevier
Background Anticancer effect of ginsenoside Rh2 has been found in various cancer cells.
However, the anticancer effect of Rh2 in endometrial cancer cells is still unclear. We aimed …
However, the anticancer effect of Rh2 in endometrial cancer cells is still unclear. We aimed …
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