Despite successful recanalization, a significant number of patients with ischemic stroke
experience impaired local brain tissue reperfusion with adverse clinical outcome. The cause …

Timely recanalization in acute ischemic stroke often results in good clinical outcomes.
However, sudden recanalization and increased blood flow into the ischemic brain tissue …

Current treatment for acute ischemic stroke aims at recanalizing the occluded blood vessel
to reperfuse ischemic brain tissue. Clot removal can be achieved pharmacologically with a …

Despite considerable research that has contributed to a better understanding of the
pathophysiology of stroke, translation of this knowledge into effective therapies has largely …

Introduction: Successful thrombectomy improves morbidity and mortality after stroke. The
present prospective, observational cohort study investigated a potential correlation between …

Objective To explore the association of poststroke baseline blood pressure with cerebral
collateral flow and functional outcome in acute ischemic patients with large vessel …

In the vascular wall, the Na, K-ATPase plays an important role in the control of arterial tone.
Through cSrc signaling, it contributes to the modulation of Ca2+ sensitivity in vascular …

The goal of reperfusion therapy for acute ischemic stroke (AIS) is to restore cerebral blood
flow through recanalization of the occluded vessel. Unfortunately, successful recanalization …

In acute ischemic stroke, abrupt vessel occlusion results in a drop in regional CBF, leading
to time-dependent compartmentalization of the ischemic brain into tissue that is irreversibly …

Background A minority of stroke patients is eligible for thrombolytic therapy. Small pilot case
series have hinted that elevation of incident arterial blood pressure might be associated with …