[HTML][HTML] Cathepsin B as a key regulator of ferroptosis in microglia following intracerebral hemorrhage
J Lu, H Li, Z Yu, C Cao, Z Xu, L Peng, JH Zhang… - Neurobiology of …, 2024 - Elsevier
Intracerebral hemorrhage (ICH) is a subtype of stroke marked by elevated mortality and
disability rates. Recently, mounting evidence suggests a significant role of ferroptosis in the …
disability rates. Recently, mounting evidence suggests a significant role of ferroptosis in the …
[HTML][HTML] Inhibition of neuronal ferroptosis protects hemorrhagic brain
Intracerebral hemorrhage (ICH) causes high mortality and morbidity, but our knowledge of
post-ICH neuronal death and related mechanisms is limited. In this study, we first …
post-ICH neuronal death and related mechanisms is limited. In this study, we first …
[HTML][HTML] Neuronal ferroptosis after intracerebral hemorrhage
S Ren, Y Chen, L Wang, G Wu - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high rates of morbidity,
mortality, and disability. It induces cell death that is responsible for the secondary brain …
mortality, and disability. It induces cell death that is responsible for the secondary brain …
[HTML][HTML] Elucidating the progress and impact of ferroptosis in hemorrhagic stroke
F Pan, W Xu, J Ding, C Wang - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Hemorrhagic stroke is a devastating cerebrovascular disease with high morbidity and
mortality, for which effective therapies are currently unavailable. Based on different bleeding …
mortality, for which effective therapies are currently unavailable. Based on different bleeding …
[HTML][HTML] Ferroptosis: underlying mechanism and the crosstalk with other modes of neuronal death after intracerebral hemorrhage
Y Cao, W Xiao, S Liu, Y Zeng - Frontiers in Cellular Neuroscience, 2023 - frontiersin.org
Intracerebral hemorrhage (ICH) is a serious cerebrovascular disease with high rates of
morbidity, mortality, and disability. Optimal treatment of ICH is a major clinical challenge, as …
morbidity, mortality, and disability. Optimal treatment of ICH is a major clinical challenge, as …
Inhibition of neuronal ferroptosis in the acute phase of intracerebral hemorrhage shows long-term cerebroprotective effects
B Chen, Z Chen, M Liu, X Gao, Y Cheng, Y Wei… - Brain Research …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a devastating subtype of stroke because it has few viable
therapeutic options to intervene against primary or second brain injury. Recently, evidence …
therapeutic options to intervene against primary or second brain injury. Recently, evidence …
[HTML][HTML] Ferroptosis, a regulated neuronal cell death type after intracerebral hemorrhage
Q Bai, J Liu, G Wang - Frontiers in Cellular Neuroscience, 2020 - frontiersin.org
Ferroptosis is a term that describes one form of regulated non-apoptotic cell death. It is
triggered by the iron-dependent accumulation of lipid peroxides. Emerging evidence …
triggered by the iron-dependent accumulation of lipid peroxides. Emerging evidence …
[HTML][HTML] Mechanism of ferroptosis and its relationships with other types of programmed cell death: insights for potential interventions after intracerebral hemorrhage
SY Zhou, GZ Cui, XL Yan, X Wang, Y Qu… - Frontiers in …, 2020 - frontiersin.org
Intracerebral hemorrhage (ICH) is a fatal cerebrovascular disease with high morbidity and
mortality, for which no effective therapies are currently available. Brain tissue damage …
mortality, for which no effective therapies are currently available. Brain tissue damage …
Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway
Z Jiang, H Yang, W Ni, X Gao, X Pei… - CNS Neuroscience …, 2024 - Wiley Online Library
Aim The class I histone deacetylases (HDACs) implicate in microglial heterogenization and
neuroinflammation following Intracerebral hemorrhage (ICH). Ferroptosis has also been …
neuroinflammation following Intracerebral hemorrhage (ICH). Ferroptosis has also been …
H3K9 trimethylation dictates neuronal ferroptosis through repressing Tfr1
T Lan, L Hu, T Sun, X Wang, Z Xiao… - Journal of Cerebral …, 2023 - journals.sagepub.com
Spontaneous intracerebral hemorrhage (ICH) is a devastating disease with high morbidity
and mortality worldwide. We have previously shown that ferroptosis contributes to neuronal …
and mortality worldwide. We have previously shown that ferroptosis contributes to neuronal …
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