Inflammatory molecular endotypes of nasal polyps derived from White and Japanese populations
T Nakayama, IT Lee, W Le, Y Tsunemi… - Journal of Allergy and …, 2022 - Elsevier
Background Emerging evidence suggests that chronic rhinosinusitis with nasal polyps
(CRSwNP) is a highly heterogeneous disease with disparate inflammatory characteristics …
(CRSwNP) is a highly heterogeneous disease with disparate inflammatory characteristics …
Whole-transcriptome sequencing reveals heightened inflammation and defective host defence responses in chronic rhinosinusitis with nasal polyps
Y Peng, XX Zi, TF Tian, B Lee, J Lum… - European …, 2019 - Eur Respiratory Soc
Introduction The pathways underlying chronic rhinosinusitis with nasal polyps (CRSwNP)
are unclear. We conducted genome-wide gene expression analysis to determine pathways …
are unclear. We conducted genome-wide gene expression analysis to determine pathways …
Distinct type 2-high inflammation associated molecular signatures of chronic rhinosinusitis with nasal polyps with comorbid asthma
M Wang, X Bu, G Luan, L Lin, Y Wang, J Jin… - Clinical and translational …, 2020 - Springer
Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and comorbid
asthma have more severe disease and are difficult to treat. However, the molecular …
asthma have more severe disease and are difficult to treat. However, the molecular …
Distinct gene expression profiles and regulation networks of nasal polyps in eosinophilic and non‐eosinophilic chronic rhinosinusitis
N Okada, T Nakayama, D Asaka… - … Forum of Allergy & …, 2018 - Wiley Online Library
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is known to have 2
phenotypes in East Asia. Eosinophilic CRSwNP (ECRSwNP), defined as tissue eosinophilia …
phenotypes in East Asia. Eosinophilic CRSwNP (ECRSwNP), defined as tissue eosinophilia …
Transcriptome analysis reveals distinct gene expression profiles in eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyps
W Wang, Z Gao, H Wang, T Li, W He, W Lv, J Zhang - Scientific Reports, 2016 - nature.com
Chronic rhinosinusitis with nasal polyps (CRSwNP), one of the most prevalent chronic
diseases, is characterized by persistent inflammation of sinonasal mucosa. However, the …
diseases, is characterized by persistent inflammation of sinonasal mucosa. However, the …
A family-based genome-wide association study of chronic rhinosinusitis with nasal polyps implicates several genes in the disease pathogenesis
Background The pathogenesis of chronic rhinosinusitis with nasal polyps is largely
unknown. Previous studies have given valuable information about genetic variants …
unknown. Previous studies have given valuable information about genetic variants …
Mechanisms and biomarkers of inflammatory endotypes in chronic rhinosinusitis without nasal polyps
Background Chronic rhinosinusitis (CRS) without nasal polyps (CRSsNP) is a common
disease that is characterized by multiple inflammatory endotypes. However, the molecular …
disease that is characterized by multiple inflammatory endotypes. However, the molecular …
[HTML][HTML] Identification of inflammatory endotypes by clinical characteristics and nasal secretion biomarkers in chronic rhinosinusitis with nasal polyps
CL Guo, RY Lu, CS Wang, JF Zhao, L Pan… - … Archives of Allergy and …, 2023 - karger.com
Introduction: The emergency of biologics and surgical techniques targeting the specific
inflammatory endotype in chronic rhinosinusitis with nasal polyps (CRSwNP) asks for …
inflammatory endotype in chronic rhinosinusitis with nasal polyps (CRSwNP) asks for …
[PDF][PDF] Cellular phenotyping of chronic rhinosinusitis with nasal polyps
H Lou, Y Meng, Y Piao, N Zhang, C Bachert, C Wang… - Rhinology, 2016 - academia.edu
Background: Defining the phenotypes of chronic rhinosinusitis with nasal polyps (CRSwNP)
with prognosis may lead to delivery of personalized treatment. This study aimed to identify …
with prognosis may lead to delivery of personalized treatment. This study aimed to identify …
Chronic rhinosinusitis with nasal polyps in older adults: clinical presentation, pathophysiology, and comorbidity
Abstract Purpose of Review Chronic rhinosinusitis and nasal polyps (CRSwNP) is a
common condition that significantly affects patients' life. This work aims to provide an up-to …
common condition that significantly affects patients' life. This work aims to provide an up-to …
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