Review of D‐dimer testing: Good, Bad, and Ugly

LA Linkins, S Takach Lapner - International Journal of …, 2017 - Wiley Online Library
D‐dimer assays are commonly used in clinical practice to exclude a diagnosis of deep vein
thrombosis or pulmonary embolism. More recently, they have been also been used to guide …

D-dimer: simple test, tough problems

JD Olson, MT Cunningham… - … of Pathology and …, 2013 - meridian.allenpress.com
Context.—D-dimer is widely used for exclusion, or as an aid in diagnosis, of venous
thromboembolism (VTE); however, the D-dimer assay methods available from …

d-Dimer for the Exclusion of Acute Venous Thrombosis and Pulmonary Embolism: A Systematic Review

PD Stein, RD Hull, KC Patel, RE Olson… - Annals of internal …, 2004 - acpjournals.org
Background: Despite extensive literature, the diagnostic role of d-dimer for deep venous
thrombosis (DVT) or pulmonary embolism (PE) remains unclear, reflecting multiple d-dimer …

[HTML][HTML] Diagnostic accuracy of D‐dimer test for exclusion of venous thromboembolism: a systematic review

M Di Nisio, A Squizzato, AWS Rutjes, HR Büller… - Journal of thrombosis …, 2007 - Elsevier
Background: The reported diagnostic accuracy of the D‐dimer test for exclusion of deep vein
thrombosis (DVT) and pulmonary embolism (PE) varies. It is unknown to what extent this is …

[HTML][HTML] D‐Dimer for venous thromboembolism diagnosis: 20 years later

M Righini, A Perrier, P De Moerloose… - Journal of thrombosis …, 2008 - Elsevier
Twenty years after its first use in the diagnostic workup of suspected venous
thromboembolism (VTE), fibrin D‐dimer (DD) testing has gained wide acceptance for ruling …

[PDF][PDF] Never ignore extremely elevated D-dimer levels: they are specific for serious illness

T Schutte, A Thijs, YM Smulders - Neth J Med, 2016 - njmonline.nl
Background: D-dimer is routinely measured as part of the clinical diagnosis algorithms for
venous thromboembolism (VTE). In these algorithms, low D-dimer cut-off values are used to …

The role of D-dimer testing in patients with suspected venous thromboembolism

D Prisco, E Grifoni - Seminars in thrombosis and hemostasis, 2009 - thieme-connect.com
ABSTRACT D-dimer, the final degradation product of cross-linked fibrin, is typically elevated
in patients with acute venous thromboembolism. With its high sensitivity and negative …

Contribution of a new, rapid, individual and quantitative automated D-dimer ELISA to exclude pulmonary embolism

P de Moerloose, S Desmarais… - Thrombosis and …, 1996 - thieme-connect.com
The performance of a new automated ELISA for a rapid, individual and quantitative
measurement of plasma D-dimer (VIDAS D-dimer) has been evaluated. First, a study of 100 …

Use of different d‐dimer levels to exclude venous thromboembolism depending on clinical pretest probability

LA Linkins, SM Bates, JS Ginsberg… - Journal of Thrombosis …, 2004 - Wiley Online Library
Currently, the same d‐dimer cut‐off point is used to define a positive result for all patients
with suspected venous thromboembolism, regardless of their pretest probability. However …

D-dimer testing for deep venous thrombosis: a metaanalysis

SW Heim, JM Schectman, MS Siadaty… - Clinical …, 2004 - academic.oup.com
Background: The use of D-dimer assays as a rule-out test for deep venous thrombosis (DVT)
is controversial. To clarify this issue we performed a systematic review of the relevant …