[HTML][HTML] Natural products targeting Nrf2/ARE signaling pathway in the treatment of inflammatory bowel disease
B Li, Y Wang, X Jiang, H Du, Y Shi, M Xiu, Y Liu… - Biomedicine & …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a special chronic intestinal inflammatory disease, which
is mainly divided into Crohn's disease (CD) and ulcerative colitis (UC). Its occurrence is a …
is mainly divided into Crohn's disease (CD) and ulcerative colitis (UC). Its occurrence is a …
[HTML][HTML] Effects of medicinal plants and phytochemicals in Nrf2 pathways during inflammatory bowel diseases and related colorectal cancer: A comprehensive review
LF Laurindo, MC de Maio, G Minniti, N de Góes Corrêa… - Metabolites, 2023 - mdpi.com
Inflammatory bowel diseases (IBDs) are related to nuclear factor erythroid 2-related factor 2
(Nrf2) dysregulation. In vitro and in vivo studies using phytocompounds as modulators of the …
(Nrf2) dysregulation. In vitro and in vivo studies using phytocompounds as modulators of the …
Natural products: experimental efficient agents for inflammatory bowel disease therapy
F Cao, J Liu, BX Sha, HF Pan - Current pharmaceutical design, 2019 - ingentaconnect.com
Inflammatory bowel disease (IBD) is a chronic, elusive disorder resulting in relapsing
inflammation of intestine with incompletely elucidated etiology, whose two representative …
inflammation of intestine with incompletely elucidated etiology, whose two representative …
The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases
M Piotrowska, M Swierczynski, J Fichna… - Pharmacological …, 2021 - Elsevier
Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …
[HTML][HTML] Triggers for the Nrf2/ARE signaling pathway and its nutritional regulation: Potential therapeutic applications of ulcerative colitis
H Liu, LJ Johnston, F Wang, X Ma - International journal of molecular …, 2021 - mdpi.com
Ulcerative colitis (UC), which affects millions of people worldwide, is characterized by
extensive colonic injury involving mucosal and submucosal layers of the colon. Nuclear …
extensive colonic injury involving mucosal and submucosal layers of the colon. Nuclear …
[HTML][HTML] Natural coumarin derivatives activating Nrf2 signaling pathway as lead compounds for the design and synthesis of intestinal anti-inflammatory drugs
LC Di Stasi - Pharmaceuticals, 2023 - mdpi.com
Nrf2 (nuclear factor erythroid 2-related factor 2) is a transcription factor related to stress
response and cellular homeostasis that plays a key role in maintaining the redox system …
response and cellular homeostasis that plays a key role in maintaining the redox system …
[HTML][HTML] Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways
Inflammatory bowel disease (IBD) refers to a group of disorders characterized by chronic
inflammation of the gastrointestinal (GI) tract. The elevated levels of nitric oxide (NO) in …
inflammation of the gastrointestinal (GI) tract. The elevated levels of nitric oxide (NO) in …
[HTML][HTML] 3-(1H-Benzo[d]imidazol-6-yl)-5-(4-fluorophenyl)-1,2,4-oxadiazole (DDO7232), a Novel Potent Nrf2/ARE Inducer, Ameliorates DSS-Induced Murine Colitis …
LL Xu, T Liu, L Wang, L Li, YF Wu, CC Li, B Di… - … medicine and cellular …, 2018 - hindawi.com
Ulcerative colitis (UC) is a common inflammatory bowel disease that can destroy the integrity
of the colon and increase the risk of colorectal cancer. Oxidative stress is one of the critical …
of the colon and increase the risk of colorectal cancer. Oxidative stress is one of the critical …
[HTML][HTML] Farrerol ameliorates TNBS-induced colonic inflammation by inhibiting ERK1/2, JNK1/2, and NF-κB signaling pathway
X Ran, Y Li, G Chen, S Fu, D He, B Huang… - International journal of …, 2018 - mdpi.com
Farrerol, a type of 2, 3-dihydro-flavonoid, is obtained from Rhododendron. Previous studies
have shown that Farrerol performs multiple biological activities, such as anti-inflammatory …
have shown that Farrerol performs multiple biological activities, such as anti-inflammatory …
[HTML][HTML] The role of Nrf2 in the pathogenesis and treatment of ulcerative colitis
S Peng, L Shen, X Yu, L Zhang, K Xu, Y Xia… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC) is a chronic inflammatory bowel disease involving mainly the
colorectal mucosa and submucosa, the incidence of which has been on the rise in recent …
colorectal mucosa and submucosa, the incidence of which has been on the rise in recent …
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