[HTML][HTML] Curcumin inhibits lung cancer invasion and metastasis by attenuating GLUT1/MT1-MMP/MMP2 pathway

H Liao, Z Wang, Z Deng, H Ren, X Li - International journal of …, 2015 - ncbi.nlm.nih.gov
Glucose transporter (GLUT) 1 is found highly expressed in malignant tumors and considered
a mediator inducing cancer metastasis. Curcumin is a natural product which exerts anti …

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and-9 and Vascular Endothelial …

SS Lin, KC Lai, SC Hsu, JS Yang, CL Kuo, JP Lin… - Cancer letters, 2009 - Elsevier
It is well known that matrix metalloproteinases (MMPs) act an important role in the invasion,
metastasis and angiogenesis of cancer cells. Agents suppressed the MMPs could inhibited …

[HTML][HTML] Curcumin inhibits the invasion of lung cancer cells by modulating the PKCα/Nox-2/ROS/ATF-2/MMP-9 signaling pathway

Z Fan, X Duan, H Cai, L Wang, M Li… - Oncology …, 2015 - spandidos-publications.com
Invasion and metastasis are the major causes of tumor-related mortality in lung cancer. It is
believed that curcumin is an effective drug possessing anti-invasive and anti-metastatic …

Role of TGF-β signaling in curcumin-mediated inhibition of tumorigenicity of human lung cancer cells

R Datta, SK Halder, B Zhang - Journal of cancer research and clinical …, 2013 - Springer
Purpose Curcumin has been shown to have potent anticancer activities like inhibition of cell
proliferation, induction of apoptosis, and suppression of angiogenesis. Transforming growth …

Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/β-catenin pathway

Y Lu, C Wei, Z Xi - In Vitro Cellular & Developmental Biology-Animal, 2014 - Springer
Curcumin, a naturally occurring phenolic compound, has a diversity of antitumor activities. It
has been previously demonstrated that curcumin can inhibit the invasion and metastasis of …

Curcumin inhibits lung cancer cell migration and invasion through Rac1-dependent signaling pathway

Q Chen, Y Zheng, D Jiao, F Chen, H Hu, Y Wu… - The Journal of nutritional …, 2014 - Elsevier
Curcumin, a natural and crystalline compound isolated from the plant Curcuma longa with
low toxicity in normal cells, has been shown to protect against carcinogenesis and prevent …

Curcumin inhibits migration and invasion of non-small cell lung cancer cells through up-regulation of miR-206 and suppression of PI3K/AKT/mTOR signaling pathway

N Wang, T Feng, X Liu, Q Liu - Acta pharmaceutica, 2020 - hrcak.srce.hr
Sažetak Curcumin has been proved to inhibit cell proliferation and induce cell apoptosis in
non-small cell lung cancer (NSCLC). However, little is known about antimetastatic effects …

[HTML][HTML] Curcumin inhibits cell proliferation and migration in NSCLC through a synergistic effect on the TLR4/MyD88 and EGFR pathways

L Zhang, X Tao, Q Fu, C Ge, R Li, Z Li… - Oncology …, 2019 - spandidos-publications.com
Despite the increasing number of available therapeutic methods, the prognosis of non‑small
cell lung cancer (NSCLC) remains poor. Furthermore, side effects are an important limiting …

Effect of curcumin and Meriva on the lung metastasis of murine mammary gland adenocarcinoma

A Ibrahim, A El-Meligy, H Fetaih, A Dessouki, G Stoica… - in vivo, 2010 - iv.iiarjournals.org
Background: Curcumin is one of the most studied natural compounds which has been used
as a feed additive for centuries. Curcumin exhibits low oral bioavailability in rodents and …

[HTML][HTML] Anticancer effects of curcumin on nude mice bearing lung cancer A549 cell subsets SP and NSP cells

X Li, S Ma, P Yang, B Sun, Y Zhang… - Oncology …, 2018 - spandidos-publications.com
Curcumin is a key polyphenolic curcuminoid extracted from the root of turmeric rhizome
Curcuma longa Linn, which is a frequently used Chinese herb for the treatment of cancer …