The role and regulation of innate immune cells is poorly understood in B-cell non-Hodgkin
lymphoma (NHL). As natural killer (NK) cells, helper innate lymphoid cells (ILCs) are …

While natural killer (NK) cells are essential players in detection and elimination of malignant
cells, these surveillance properties can be compromised by cancer cells. Since NK cell …

Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not
possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue …

Strategies of manipulating immunosuppressive regulatory T cells (Treg) in cancer patients
are currently evaluated in clinical trials. Treg suppress immune responses of tumor‐specific …

The tumor microenvironment in B-cell non-Hodgkin lymphoma (NHL) comprises not only
malignant cells but also significant numbers of normal immune cells. The intratumoral …

The world of lymphocytes has recently expanded. A group of cells, innate lymphoid cells
(ILC), has been defined. It includes lymphoid cells that have been known for decades, such …

Purpose Targeting cancer cells by modulating the immune system has become an important
new therapeutic option in many different malignancies. Inhibition of CTLA4/B7 and …

Innate lymphoid cells (ILCs) are an emerging family of innate immune cells and have been
found to have an important role in infection, inflammation and tissue repair. In particular …

Innate lymphoid cells (ILC) including NK cells (cytotoxic) and the recently identified “helper”
ILC1, ILC2 and ILC3, play an important role in innate defenses against pathogens. Notably …

Innate lymphoid cells (ILCs) were found to be developmentally related to natural killer (NK)
cells. In humans, they are mostly located in “barrier” tissues where they contribute to innate …