Importance Patterns-of-failure studies suggest that in metastatic non–small-cell lung cancer
(NSCLC) sites of gross disease at presentation are the first to progress when treated with …

Introduction: The purpose of this study was to evaluate whether consolidation chemotherapy
(CCT) after concurrent chemo-radiotherapy is beneficial for patients with locally advanced …

PURPOSE Our previously published findings reported that local consolidative therapy (LCT)
with radiotherapy or surgery improved progression-free survival (PFS) and delayed new …

Background Evidence from retrospective studies suggests that disease progression after first-
line chemotherapy for metastatic non-small-cell lung cancer (NSCLC) occurs most often at …

Introduction Although most NSCLC patients with sensitizing epidermal growth factor
receptor (EGFR) mutations have an impressive initial response, the vast majority has …

Introduction: Stereotactic ablative radiotherapy is a guideline-recommended treatment for
early stage non–small-cell lung cancer. We report on incidence and salvage of local …

Background Standard therapy for metastatic non small cell lung cancer (NSCLC) includes
palliative systemic chemotherapy and/or radiotherapy. Recent studies of patients with limited …

Introduction: Outcomes data treating patients with oligometastatic (⩽ 5 metastases) non-
small cell lung carcinoma (NSCLC) with hypofractionated image-guided radiotherapy …

Background Local consolidative therapy (LCT) to optimize disease control is an evolving
management paradigm in non–small-cell lung cancer (NSCLC) patients who present with a …

Purpose To provide guidance to physicians and patients with regard to the use of definitive
external beam radiation therapy (RT) in locally advanced non-small cell lung cancer (LA …