Protective Effect of Shengmaiyin in Myocardial Hypertrophy‐Induced Rats: A Genomic Analysis by 16S rDNA

S Ming, M Kan, L Liu, Z Zhang, X Liu… - Evidence‐Based …, 2022 - Wiley Online Library
Background. The gut‐cardiac axis theory provides new insights into the complex
mechanisms of cardiac hypertrophy and provides new therapeutic targets. Cardiac …

Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway

Y Cui, F Zhang, W Xu, Z Li, J Zou, P Gao… - … Medicine and Therapies, 2023 - Springer
Abstract Background Coronary Artery Disease (CAD) is primarily caused by inflammation
which is closely linked to the gut microbiota. Si-Miao-Yong-An (SMYA) decoction is a …

Shenxiang Suhe pill improves cardiac function through modulating gut microbiota and serum metabolites in rats after acute myocardial infarction

X Zhong, J Yan, X Wei, T Xie, Z Zhang… - Pharmaceutical …, 2024 - Taylor & Francis
Abstract Context Shenxiang Suhe pill (SXSH), a traditional Chinese medicine, is clinically
effective against coronary heart disease, but the mechanism of cardiac-protective function is …

Shengmai Yin formula exerts cardioprotective effects on rats with chronic heart failure via regulating linoleic acid metabolism

S Wang, J Gan, J Li, Y Wang, J Zhang, L Song… - Prostaglandins & Other …, 2022 - Elsevier
The objective of this study was to investigate the protective effects of Shengmai Yin (SMY)
on rats with chronic heart failure (CHF). Sprague‐Dawley rats were used to establish a CHF …

Signature network-based survey of the effects of a traditional Chinese medicine on heart failure

Y Wu, M Wang, J Xu, J Wei, H Yang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance Heart failure (HF) after myocardial infarction (MI) is one of
the most common disabling and painful diseases. A traditional Chinese medicine (TCM) …

Qige Huxin Formula Attenuates Isoprenaline‐Induced Cardiac Fibrosis in Mice via Modulating Gut Microbiota and Protecting Intestinal Integrity

L Shi, X Du, B Zuo, J Hu, W Cao - … ‐Based Complementary and …, 2022 - Wiley Online Library
Background. The composition and metabolic activities of gut microbiota are strongly
interconnected with cardiac fibrosis (CF) and heart failure (HF). Qige Huxin formula (QHF), a …

Shengmai San Ameliorates Myocardial Dysfunction and Fibrosis in Diabetic db/db Mice

J Zhao, TT Cao, J Tian, H Chen… - Evidence‐Based …, 2016 - Wiley Online Library
In this study, we mainly investigated the effects of Shengmai San (SMS) on diabetic
cardiomyopathy (DCM) in db/db mice. The db/db mice were randomly divided into model …

The Protective Effect of Sheng Mai Yin on Diabetic Cardiomyopathy via NLRP3/Caspase‐1 Pathway

JY Li, CC Zhao, JF Peng, M Zhang… - Evidence‐Based …, 2022 - Wiley Online Library
Sheng Mai Yin (SMY) has therapeutic effects on myocardial infarction (MI), heart failure (HF),
diabetic cardiomyopathy (DCM), and myocarditis. To study whether SMY can relieve …

Effect and mechanism of Qing Gan Zi Shen decoction on heart damage induced by obesity and hypertension

S Zhang, Z Liu, H Zhang, X Zhou, X Wang… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Qing Gan Zi Shen Decoction (QGZS) is a
traditional Chinese formula. It has been extensively used for decades in the treatment of …

Exploring the mechanism of Shengmai Yin for coronary heart disease based on systematic pharmacology and chemoinformatics

Y Jiang, Q He, T Zhang, W Xiang, Z Long… - Bioscience …, 2020 - portlandpress.com
Objective: To explore the mechanism of Shengmai Yin (SMY) for coronary heart disease
(CHD) by systemic pharmacology and chemoinformatics. Methods: Traditional Chinese …