The gut microbiome, endocannabinoids and metabolic disorders

FA Iannotti, V Di Marzo - Journal of Endocrinology, 2021 - joe.bioscientifica.com
Two complex systems are emerging as being deeply involved in the control of energy
metabolism. The intestinal microbiota, with its warehouse of genes, proteins and small …

[HTML][HTML] Endocannabinoids—at the crossroads between the gut microbiota and host metabolism

PD Cani, H Plovier, M Van Hul, L Geurts… - Nature Reviews …, 2016 - nature.com
Various metabolic disorders are associated with changes in inflammatory tone. Among the
latest advances in the metabolism field, the discovery that gut microorganisms have a major …

Lifestyle and metabolic syndrome: contribution of the endocannabinoidome

V Di Marzo, C Silvestri - Nutrients, 2019 - mdpi.com
Lifestyle is a well-known environmental factor that plays a major role in facilitating the
development of metabolic syndrome or eventually exacerbating its consequences. Various …

Cannabinoid signalling regulates inflammation and energy balance: the importance of the brain–gut axis

NL Cluny, RA Reimer, KA Sharkey - Brain, behavior, and immunity, 2012 - Elsevier
Energy balance is controlled by centres of the brain which receive important inputs from the
gastrointestinal tract, liver, pancreas, adipose tissue and skeletal muscle, mediated by many …

Gut microbiota and oleoylethanolamide in the regulation of intestinal homeostasis

C De Filippo, A Costa, MV Becagli… - Frontiers in …, 2023 - frontiersin.org
A vast literature strongly suggests that the endocannabinoid (eCB) system and related
bioactive lipids (the paracannabinoid system) contribute to numerous physiological …

Rapid and concomitant gut microbiota and endocannabinoidome response to diet-induced obesity in mice

S Lacroix, F Pechereau, N Leblanc, B Boubertakh… - …, 2019 - Am Soc Microbiol
The intestinal microbiota and the expanded endocannabinoid (eCB) system, or
endocannabinoidome (eCBome), have both been implicated in diet-induced obesity and …

The microbiome and gut endocannabinoid system in the regulation of stress responses and metabolism

RK Srivastava, B Lutz, I Ruiz de Azua - Frontiers in cellular …, 2022 - frontiersin.org
The endocannabinoid system, with its receptors and ligands, is present in the gut epithelium
and enteroendocrine cells, and is able to modulate brain functions, both indirectly through …

Obesity affects the microbiota–gut–brain axis and the regulation thereof by endocannabinoids and related mediators

N Forte, AC Fernández-Rilo, L Palomba… - International Journal of …, 2020 - mdpi.com
The hypothalamus regulates energy homeostasis by integrating environmental and internal
signals to produce behavioral responses to start or stop eating. Many satiation signals are …

Glucose metabolism: focus on gut microbiota, the endocannabinoid system and beyond

PD Cani, L Geurts, S Matamoros, H Plovier… - Diabetes & …, 2014 - Elsevier
The gut microbiota is now considered as a key factor in the regulation of numerous
metabolic pathways. Growing evidence suggests that cross-talk between gut bacteria and …

Modulatory role of the endocannabinoidome in the pathophysiology of the gastrointestinal tract

J Lian, I Casari, M Falasca - Pharmacological Research, 2022 - Elsevier
Abstract Originating from Eastern Asia, the plant Cannabis sativa has been used for
centuries as a medicinal treatment. The unwanted psychotropic effects of one of its major …