Clonal haematopoiesis of indeterminate potential predicts incident cardiac arrhythmias

A Schuermans, C Vlasschaert, V Nauffal… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims Clonal haematopoiesis of indeterminate potential (CHIP), the
age-related expansion of blood cells with preleukemic mutations, is associated with …

Clonal haematopoiesis of indeterminate potential: associations with heart failure incidence, clinical parameters and biomarkers

C Shi, JP Aboumsallem, N Suthahar… - European Journal of …, 2023 - Wiley Online Library
Aim We aimed to analyse the association of clonal haematopoiesis of indeterminate
potential (CHIP) with incident heart failure (HF) in a European population cohort. Methods …

[PDF][PDF] Clonal haematopoiesis of indeterminate potential and atrial fibrillation: an East Asian cohort study

HJ Ahn, HY An, G Ryu, J Lim, C Sun… - European Heart …, 2024 - drive.google.com
Both clonal haematopoiesis of indeterminate potential (CHIP) and atrial fibrillation (AF) are
age-related conditions. This study investigated the potential role of CHIP in the development …

Association of mutations contributing to clonal hematopoiesis with prognosis in chronic ischemic heart failure

L Dorsheimer, B Assmus, T Rasper… - JAMA …, 2019 - jamanetwork.com
Importance Somatic mutations causing clonal expansion of hematopoietic cells (clonal
hematopoiesis of indeterminate potential [CHIP]) are increased with age and associated …

Clonal hematopoiesis and risk of progression of heart failure with reduced left ventricular ejection fraction

DA Pascual-Figal, A Bayes-Genis, M Díez-Díez… - Journal of the American …, 2021 - jacc.org
Background Clonal hematopoiesis driven by somatic mutations in hematopoietic cells,
frequently called clonal hematopoiesis of indeterminate potential (CHIP), has been …

Association of clonal hematopoiesis with incident heart failure

B Yu, MB Roberts, LM Raffield, SM Zekavat… - Journal of the American …, 2021 - jacc.org
Background Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as
clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2 …

Clonal hematopoiesis of indeterminate potential predicts adverse outcomes in patients with atherosclerotic cardiovascular disease

ED Gumuser, A Schuermans, SMJ Cho… - Journal of the American …, 2023 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …

[HTML][HTML] Association of clonal hematopoiesis of indeterminate potential with incident heart failure with preserved ejection fraction

AP Reiner, MB Roberts, MC Honigberg, C Kooperberg… - medRxiv, 2023 - ncbi.nlm.nih.gov
Background: Clonal hematopoiesis of indeterminate potential (CHIP) was recently identified
as a risk factor for incident heart failure (HF). Whether CHIP is associated selectively with …

Cardiovascular disease among patients with AML and CHIP-related mutations

O Calvillo-Argüelles, A Schoffel, JM Capo-Chichi… - Cardio Oncology, 2022 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP) is a novel
cardiovascular disease (CVD) risk factor in individuals without acute myeloid leukemia …

Clonal haematopoiesis of indeterminate potential: intersections between inflammation, vascular disease and heart failure

L Mooney, CS Goodyear, T Chandra… - Clinical …, 2021 - portlandpress.com
Ageing is a major risk factor for the development of cardiovascular disease (CVD) and
cancer. Whilst the cumulative effect of exposure to conventional cardiovascular risk factors is …