Nicotine dose–concentration relationship and pregnancy outcomes in rat: biologic plausibility and implications for future research

J Hussein, S Farkas, Y MacKinnon, RE Ariano… - Toxicology and applied …, 2007 - Elsevier
Cigarette smoke (CS) exposure during pregnancy can lead to profound adverse effects on
fetal development. Although CS contains several thousand chemicals, nicotine has been …

Prenatal cigarette smoke exposure: pregnancy outcome and gestational changes in plasma nicotine concentration, hematocrit, and carboxyhemoglobin in a newly …

S Farkas, J Hussein, RE Ariano, DS Sitar… - Toxicology and applied …, 2006 - Elsevier
Epidemiological studies support an association between perinatal cigarette smoke (CS)
exposure and a number of severe pre-and postnatal complications. However, the …

Long-term consequences of fetal and neonatal nicotine exposure: a critical review

JE Bruin, HC Gerstein, AC Holloway - Toxicological sciences, 2010 - academic.oup.com
Cigarette smoking during pregnancy is associated with numerous obstetrical, fetal, and
developmental complications, as well as an increased risk of adverse health consequences …

Nicotine exposure throughout early development promotes nicotine self-administration in adolescent mice and induces long-lasting behavioural changes

V Chistyakov, N Patkina, A Tammimäki, R Talka… - European journal of …, 2010 - Elsevier
Maternal cigarette smoking during pregnancy can result in behavioural problems of the
offspring. Although the causative agent in tobacco smoke that leads to these aberrations is …

In utero nicotine exposure causes persistent, gender-dependant changes in locomotor activity and sensitivity to nicotine in C57Bl/6 mice

JR Pauly, JA Sparks, KF Hauser, TH Pauly - International Journal of …, 2004 - Elsevier
Maternal cigarette smoking during pregnancy can result in a wide variety of adverse fetal
outcomes, ranging from preterm delivery and low birth weight, to sudden infant death …

Effects of nicotine during pregnancy: human and experimental evidence

R Wickstrom - Current neuropharmacology, 2007 - ingentaconnect.com
Prenatal exposure to tobacco smoke is a major risk factor for the newborn, increasing
morbidity and even mortality in the neonatal period but also beyond. As nicotine addiction is …

Chronic nicotine induces growth retardation in neonatal rat pups

LZ Huang, SH Hsiao, J Trzeciakowski, GD Frye… - Life sciences, 2006 - Elsevier
In the United State, 20% of pregnant women smoke. One of the most consistent adverse
outcomes is reduced birth weight in the off-spring. Animal studies using chronic nicotine, the …

Adverse effects of perinatal nicotine exposure on reproductive outcomes

MK Wong, NG Barra, N Alfaidy, DB Hardy… - …, 2015 - rep.bioscientifica.com
Nicotine exposure during pregnancy through cigarette smoking, nicotine replacement
therapies or e-cigarette use continues to be a widespread public health problem, impacting …

Prenatal nicotine exposure modifies behavior of mice through early development

JS Ajarem, M Ahmad - Pharmacology Biochemistry and Behavior, 1998 - Elsevier
Studies in humans and animal models (including rodents) have revealed lasting behavioral
and cognitive impairments in offspring prenatally exposed to nicotine. Offspring of pregnant …

Increased nicotine self-administration following prenatal exposure in female rats

ED Levin, S Lawrence, A Petro, K Horton… - Pharmacology …, 2006 - Elsevier
There is a significant association between maternal cigarette smoking during pregnancy and
greater subsequent risk of smoking in female offspring. In animal models, prenatal nicotine …