Background Depression is one of the most common psychiatric disorders worldwide. Many
antidepressant drugs are only effective for specific patients and their long-term use can lead …

Ginsenoside Rb1 (Rb1), an important bioactive ingredient of Panax ginseng, has potent
neuroprotective effects. The objective of the study is to elucidate the impact of Rb1 treatment …

Major depression is a common neuropsychiatric disease with high lifetime prevalence and
high incidence of suicide. This study aimed to evaluate the antidepressant effects of …

Depression is a common stress disability disorder that affects higher mental functions
including emotion, cognition, and behavior. It may be mediated by inflammatory cytokines …

Introduction The most striking feature of depression is sadness and a loss of interest in
activities, which represents a major cause of disability globally. Therefore, it is necessary to …

Depression is one of the most prevalent and crucial public health problem connected to
significant mortality and co-morbidity. Recently, numerous studies suggested that dietary …

Evidence shows that inflammatory responses may encompass the onset of severe
depressive illness. Traditionally used licorice contains 18β-glycyrrhetinic acid (18βGA) …

Objective To investigate the ameliorating effect of ginsenoside Rg1 on the depression-like
behaviors induced by chronic restraint stress (CRS) in rats and the underlying mechanisms …

Background Depression, a global neuropsychiatric disorder, brings a serious burden to
patients and society as its incidence continues to rise. Berberine is one of the main …

Depression-like behaviors caused by chronic stress are related to inflammation and
microglia activation. Antidepressant therapy may contribute to inhibiting inflammation …