AIMS: The “accelerator hypothesis” postulates that metabolic syndrome (MS) factors—
overweight and insulin resistance—increase functional demand on islets, accelerating …

Diabetes poses a significant threat to public health. In the last 30 years, the worldwide
incidence of type 2 diabetes mellitus (T2DM) has increased drastically among adolescents …

Abstract Aims/hypothesis South Asians in general, and Asian Indians in particular, have
higher risk of type 2 diabetes compared with white Europeans, and a younger age of onset …

Accumulating data suggest that type 2 diabetes mellitus (T2DM) in younger people (aged<
40 years), referred to as young-onset T2DM, has a more rapid deterioration of β-cell function …

AIMS: The aim of this study was to evaluate the relative importance of insulin sensitivity (SI),
and the first (1st ISEC) and second phase insulin secretion (2nd ISEC) in the development of …

The prevalence of diabetes, especially Type 2 diabetes mellitus (T2DM), is increasing
markedly throughout the world, including in China. Because T2DM and its complications are …

Background There is little data on the incidence of diabetes complications in young onset
type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in non European populations. Methods …

OBJECTIVE To investigate the relationship between fasting insulin levels and metabolic risk
factors (MRFs) in type 2 diabetic patients at the first clinic/hospital visit in Japan over the …

Aim: This study examined β-cell function and insulin resistance (homeostasis model
assessment-insulin resistance [HOMA-IR]) in Asian Indian youth with type 2 diabetes …

The prevalence of type 2 diabetes mellitus (T2DM) is increasing in young Asian adults;
however, little is known about the associated clinical characteristics and the prevalence of …