Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast …
WB Fang, M Medrano, P Cote, M Portsche… - Frontiers in …, 2023 - frontiersin.org
Background/Introduction As the most common form of pre-invasive breast cancer, ductal
carcinoma in situ (DCIS) affects over 50,000 women in the US annually. Despite …
carcinoma in situ (DCIS) affects over 50,000 women in the US annually. Despite …
Genomic landscape of ductal carcinoma in situ and association with progression
Purpose The detection rate of breast ductal carcinoma in situ (DCIS) has increased
significantly, raising the concern that DCIS is overdiagnosed and overtreated. Therefore …
significantly, raising the concern that DCIS is overdiagnosed and overtreated. Therefore …
Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
Ductal carcinoma in situ (DCIS) is the most common precursor of invasive breast cancer
(IBC), with variable propensity for progression. We perform multiscale, integrated molecular …
(IBC), with variable propensity for progression. We perform multiscale, integrated molecular …
Progression-specific genes identified in microdissected formalin-fixed and paraffin-embedded tissue containing matched ductal carcinoma in situ and invasive ductal …
S Schultz, H Bartsch, K Sotlar, K Petat-Dutter… - BMC medical …, 2018 - Springer
Background The transition from ductal carcinoma in situ (DCIS) to invasive breast carcinoma
(IBC) is an important step during breast carcinogenesis. Understanding its molecular …
(IBC) is an important step during breast carcinogenesis. Understanding its molecular …
[HTML][HTML] Epithelial cells captured from ductal carcinoma in situ reveal a gene expression signature associated with progression to invasive breast cancer
EV Elias, NP De Castro, PHB Pineda, CS Abuázar… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Breast cancer biomarkers that can precisely predict the risk of progression of non-invasive
ductal carcinoma in situ (DCIS) lesions to invasive disease are lacking. The identification of …
ductal carcinoma in situ (DCIS) lesions to invasive disease are lacking. The identification of …
Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ
M Tokura, J Nakayama, M Prieto-Vila, S Shiino… - Cancer Research, 2022 - AACR
Ductal carcinoma in situ (DCIS) is a precursor to invasive breast cancer. The frequency of
DCIS is increasing because of routine mammography; however, the biological features and …
DCIS is increasing because of routine mammography; however, the biological features and …
Learning to distinguish progressive and non-progressive ductal carcinoma in situ
AK Casasent, MM Almekinders, C Mulder… - Nature Reviews …, 2022 - nature.com
Ductal carcinoma in situ (DCIS) is a non-invasive breast neoplasia that accounts for 25% of
all screen-detected breast cancers diagnosed annually. Neoplastic cells in DCIS are …
all screen-detected breast cancers diagnosed annually. Neoplastic cells in DCIS are …
ID2 and GJB2 promote early-stage breast cancer progression by regulating cancer stemness
Purpose Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer which could
progress to or recur as invasive breast cancer. The underlying molecular mechanism of …
progress to or recur as invasive breast cancer. The underlying molecular mechanism of …
Progression of ductal carcinoma in situ to invasive breast cancer is associated with gene expression programs of EMT and myoepithelia
ES Knudsen, A Ertel, E Davicioni, J Kline… - Breast cancer research …, 2012 - Springer
Ductal carcinoma in situ (DCIS) is a precursor lesion that can gives rise to invasive breast
cancer (IBC). It has been proposed that both the nature of the lesion and the tumor …
cancer (IBC). It has been proposed that both the nature of the lesion and the tumor …
Human ductal carcinoma in situ: advances and future perspectives
F Behbod, JH Chen… - Cold Spring …, 2023 - perspectivesinmedicine.cshlp.org
Due to widespread adoption of screening mammography, there has been a significant
increase in new diagnoses of ductal carcinoma in situ (DCIS). However, DCIS outcomes …
increase in new diagnoses of ductal carcinoma in situ (DCIS). However, DCIS outcomes …