The role of triterpenes in the management of diabetes mellitus and its complications

J Nazaruk, M Borzym-Kluczyk - Phytochemistry Reviews, 2015 - Springer
Diabetes mellitus is a chronic metabolic disease which is a serious global problem. In 2010
an estimated 285 million people had diabetes and within the next 20 years this value is …

Therapeutic potentials of triterpenes in diabetes and its associated complications

S Putta, N Sastry Yarla, E Kumar Kilari… - Current topics in …, 2016 - ingentaconnect.com
Diabetes is a major chronic metabolic disorder globally and around of 285 million people
are affected by the disease and the number is expected to double in the next two decades …

In vitro and in vivo antidiabetic potential of monoterpenoids: An update

LT Al Kury, A Abdoh, K Ikbariah, B Sadek, M Mahgoub - Molecules, 2021 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic condition characterized by persistent
hyperglycemia due to insufficient insulin levels or insulin resistance. Despite the availability …

Anti-diabetic potential of plant-based pentacyclic triterpene derivatives: Progress made to improve efficacy and bioavailability

M Oboh, L Govender, M Siwela, BN Mkhwanazi - Molecules, 2021 - mdpi.com
Diabetes mellitus (DM) results from the inability of the pancreas to produce sufficient insulin
or weakened cellular response to the insulin produced, which leads to hyperglycemia …

Targeting type II diabetes with plant terpenes: The new and promising antidiabetic therapeutics

SK Panigrahy, R Bhatt, A Kumar - Biologia, 2021 - Springer
Type II diabetes is a metabolic disorder characterized by hyperglycemia arising from
defective insulin signaling. Several synthetic drugs are being used for diabetes treatment …

Phytochemicals and their effective role in the treatment of diabetes mellitus: a short review

SL Teoh, S Das - Phytochemistry Reviews, 2018 - Springer
There is a global increase in the incidence of diabetes mellitus (DM). Hyperglycemia is one
of the prevailing conditions which gives rise to various diabetic complications. The major …

The pentacyclic triterpenoids in herbal medicines and their pharmacological activities in diabetes and diabetic complications

A Alqahtani, K Hamid, A Kam, KH Wong… - Current Medicinal …, 2013 - ingentaconnect.com
Pentacyclic triterpenoids including the oleanane, ursane and lupane groups are widely
distributed in many medicinal plants, such as Glycyrrhiza species, Gymnema species …

Biochemical basis of the antidiabetic activity of oleanolic acid and related pentacyclic triterpenes

JM Castellano, A Guinda, T Delgado, M Rada… - Diabetes, 2013 - Am Diabetes Assoc
Oleanolic acid (OA), a natural component of many plant food and medicinal herbs, is
endowed with a wide range of pharmacological properties whose therapeutic potential has …

Antidiabetic potential of monoterpenes: A case of small molecules punching above their weight

S Habtemariam - International Journal of Molecular Sciences, 2017 - mdpi.com
Monoterpenes belong to the terpenoids class of natural products and are bio-synthesized
through the mevalonic acid pathway. Their small molecular weight coupled with high non …

[HTML][HTML] An overview of herbal products and secondary metabolites used for management of type two diabetes

A Ota, NP Ulrih - Frontiers in pharmacology, 2017 - frontiersin.org
Diabetes mellitus is a common effect of uncontrolled high blood sugar and it is associated
with long-term damage, dysfunction, and failure of various organs. In the adult population …