Mecanismos epigenéticos em hepatoblastomas: análise do transcriptoma e sua regulação
por metilação de DNA. Tumores hepáticos em crianças são raros, representando 1-4% de …

Hepatoblastoma is an embryonal liver tumor carrying few genetic alterations. We previously
disclosed in hepatoblastomas a genome-wide methylation dysfunction, characterized by …

Background Hepatoblastoma (HB) is a rare embryonal liver tumor of children. Although
intrinsic biological differences between tumors can affect prognosis, few groups have …

Primary liver cancers are rare in children, and the most common type is hepatoblastoma
(HB), an embryonal tumor with histological features that resemble different stages of liver …

Hepatoblastoma is a malignant embryonal tumor with multiple differentiation modes and is
the clearest liver malignancy in children. However, little is known about genetic and …

O hepatoblastoma, câncer de fígado mais comum na infância, é um tumor embrionário que
se supõe surgir da interrupção da diferenciação hepática durante a embriogênese. O …

Hepatoblastomas are uncommon embryonal liver tumors accounting for approximately 80%
of childhood hepatic cancer. We hypothesized that epigenetic changes, including DNA …

Hepatoblastoma comprises only 1% of all cancers in childhood. Because of its low
frequency, a small number of prognostic factors are described in hepatoblastoma and most …

Hepatoblastoma (HB) is the most common malignant liver tumor in children. Abnormal
activation of the Wnt/β-catenin signaling pathway plays an important role in the formation …

Background Aberrant methylation at imprinted differentially methylated regions (DMRs) in
human 11p15. 5 has been reported in many tumors including hepatoblastoma. However, the …