Safety and tolerability of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in oncology
RR Shah, DR Shah - Drug safety, 2019 - Springer
Tyrosine kinase inhibitors (TKIs) that target epidermal growth factor receptor (EGFR) have
dramatically improved progression-free survival in non-small-cell lung cancer (NSCLC) …
dramatically improved progression-free survival in non-small-cell lung cancer (NSCLC) …
Management of egfr tki—Induced Dermatologic Adverse Events
B Melosky, NB Leighl, J Rothenstein, R Sangha… - Current …, 2015 - mdpi.com
Targeting the epidermal growth factor receptor (EGFR) pathway has become standard
practice for the treatment of advanced non-small-cell lung cancer. Compared with …
practice for the treatment of advanced non-small-cell lung cancer. Compared with …
Management of epidermal growth factor receptor tyrosine kinase inhibitor‐related cutaneous and gastrointestinal toxicities
DCW Aw, EH Tan, TM Chin, HL Lim… - Asia‐Pacific Journal …, 2018 - Wiley Online Library
Patients with advanced stage non–small cell lung cancer with sensitizing epidermal growth
factor receptor (EGFR) mutations using EGFR tyrosine kinase inhibitors (TKIs) such as …
factor receptor (EGFR) mutations using EGFR tyrosine kinase inhibitors (TKIs) such as …
Management of common toxicities in metastatic NSCLC related to anti-lung cancer therapies with EGFR–TKIs
B Melosky, V Hirsh - Frontiers in oncology, 2014 - frontiersin.org
Tyrosine kinase inhibitors (TKIs) against the epidermal growth factor receptor (EGFR) are
the standard of care treatment in non-small cell lung cancer (NSCLC). TKIs are used first line …
the standard of care treatment in non-small cell lung cancer (NSCLC). TKIs are used first line …
Skin toxicities associated with epidermal growth factor receptor inhibitors
T Li, R Perez-Soler - Targeted oncology, 2009 - Springer
The use of epidermal growth factor receptor (EGFR) inhibitors in several epithelial tumors
has increased considerably in recent years. Currently, they are approved in non-small cell …
has increased considerably in recent years. Currently, they are approved in non-small cell …
Mechanisms of cutaneous toxicities to EGFR inhibitors
ME Lacouture - Nature Reviews Cancer, 2006 - nature.com
The increased target specificity of epidermal growth factor receptor (EGFR) inhibitors
(EGFRIs) is associated with the reduction or abolition of nonspecific and haematopoietic …
(EGFRIs) is associated with the reduction or abolition of nonspecific and haematopoietic …
[HTML][HTML] Managing treatment-related adverse events associated with EGFR tyrosine kinase inhibitors in advanced non-small-cell lung cancer
V Hirsh - Current Oncology, 2011 - ncbi.nlm.nih.gov
Non-small-cell lung cancer (nsclc) has the highest prevalence of all types of lung cancer,
which is the second most common cancer and the leading cause of cancer-related mortality …
which is the second most common cancer and the leading cause of cancer-related mortality …
Targeting the epidermal growth factor receptor in solid tumors: focus on safety
Introduction: Inhibition of the EGFR has emerged as a promising anticancer strategy, offering
improved efficacy and quality of life for patients affected by tumors. The overall level of …
improved efficacy and quality of life for patients affected by tumors. The overall level of …
Cutaneous side effects of epidermal growth factor receptor inhibitors: clinical presentation, pathogenesis, and management
JC Hu, P Sadeghi, LC Pinter-Brown, S Yashar… - Journal of the American …, 2007 - Elsevier
The growing investigation and use of epidermal growth factor receptor (EGFR) inhibitors in
anticancer therapy has been motivated by their specificity for EGFR, which improves their …
anticancer therapy has been motivated by their specificity for EGFR, which improves their …
Epidermal growth factor receptor inhibitor–associated cutaneous toxicities: an evolving paradigm in clinical management
TJ Lynch Jr, ES Kim, B Eaby, J Garey, DP West… - The …, 2007 - academic.oup.com
Epidermal growth factor receptor inhibitors (EGFRIs) have demonstrated improved overall
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …
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