Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Although a large number of new drug molecules with varied therapeutic potentials have
been discovered in the recent decade, yet most of them are still in developmental process …

The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …

ABSTRACT A number of new molecular entities (NMEs) selected for full‐scale development
based on their safety and pharmacological data suffer from undesirable physicochemical …

A drug's aqueous solubility is defined as the ability to dissolve in a particular solvent, and it
is currently a major hurdle in bringing new drug molecules to the market. According to some …

One of the major problems associated with poorly soluble drugs is very low bioavailability.
The problem is even more complex for drugs like itraconazole, simvastatin, and …

In the past few decades, nanotechnology has been used to develop various nano-based
systems to facilitate the delivery of therapeutic and imaging agents for various medical …

Nanosuspension technology and its applications in drug delivery Page 1 168 Asian Journal of
Pharmaceutics - July-September 2009 INTRODUCTION One of the main problems responsible …

Nanoparticulate systems have emerged as prevalent drug delivery systems over the past
few decades. These delivery systems (such as liposomes, emulsions, nanocrystals, and …

The advancement in medical sciences and perturbing limitations of some conventional drug
delivery systems have triggered extensive research in nanomedicine, and there have been …