Traumatic brain injury (TBI) has been linked to dementia and chronic neurodegeneration.
Described initially in boxers and currently recognized across high contact sports, the …

This review recounts the definitions and research evidence supporting the multifaceted roles
of neuroinflammation in the injured brain following trauma. We summarise the literature …

There is significant interest in understanding inflammatory responses within the brain and
spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are …

Inflammation is a key component of host defence responses to peripheral inflammation and
injury, but it is now also recognized as a major contributor to diverse, acute and chronic …

Traumatic brain injury (TBI) elicits a complex secondary injury response, with
neuroinflammation as a crucial central component. Long thought to be solely a deleterious …

It has long been suggested that prior traumatic brain injury (TBI) increases the subsequent
incidence of chronic neurodegenerative disorders, including Alzheimer disease, Parkinson …

Ischaemic stroke involves the rapid onset of focal neurological dysfunction, most commonly
due to an arterial blockage in a specific region of the brain. Stroke is a leading cause of …

Brain inflammation is a complex cellular and molecular response to stress, injury or infection
of the CNS in attempt to defend against insults, clear dead and damaged neurons and return …

Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and
activation of systemic immunity with the capacity to exacerbate neuropathology and …

Inflammation of the central nervous system (CNS)(neuroinflammation) is now recognized to
be a feature of all neurological disorders. In multiple sclerosis, there is prominent infiltration …