Quercetin nanoparticle complex attenuated diabetic nephropathy via regulating the expression level of ICAM-1 on endothelium

F Tong, S Liu, B Yan, X Li, S Ruan… - International Journal of …, 2017 - Taylor & Francis
The purpose of the study was to reveal the therapeutic effect of quercetin (QUE) nanoparticle
complex on diabetic nephropathy (DN) by regulating the expression of intercellular …

Investigating the molecular mechanism of quercetin protecting against podocyte injury to attenuate diabetic nephropathy through network pharmacology …

X Ma, C Hao, M Yu, Z Zhang, J Huang… - Evidence‐Based …, 2022 - Wiley Online Library
Quercetin (QUE), a health supplement, can improve renal function in diabetic nephropathy
(DN) rats by ameliorating podocyte injury. Its clinical trial for renal insufficiency in advanced …

[HTML][HTML] Therapeutic investigation of quercetin nanomedicine in a zebrafish model of diabetic retinopathy

S Wang, S Du, W Wang, F Zhang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is progressive damage to the retina and it's caused by damage to
the blood-retinal barrier. Quercetin has pleiotropic action like anti-oxidant, regulation cell …

Quercetin attenuates the proliferation, inflammation, and oxidative stress of high glucose-induced human mesangial cells by regulating the miR-485-5p/YAP1 pathway

H Wan, Y Wang, Q Pan, X Chen… - International …, 2022 - journals.sagepub.com
Background Diabetic nephropathy (DN) is a kidney damage caused by diabetes and the
main cause of end-stage renal disease. However, the current treatment of DN has many …

Quercetin prevents chronic kidney disease on mesangial cells model by regulating inflammation, oxidative stress, and TGF-β1/SMADs pathway

W Widowati, S Prahastuti, R Tjokropranoto… - PeerJ, 2022 - peerj.com
Background Chronic kidney disease (CKD) happens due to decreasing kidney function.
Inflammation and oxidative stress have been shown to result in the progression of CKD …

Stabilized-chitosan selenium nanoparticles efficiently reduce renal tissue injury and regulate the expression pattern of aldose reductase in the diabetic-nephropathy …

SI Khater, AAR Mohamed, AH Arisha, LLM Ebraheim… - Life Sciences, 2021 - Elsevier
One of the global alarming prevalent metabolic diseases is Type 2 diabetes mellitus (T2DM)
than other diabetes and sustains a substantial burden on public and healthcare systems …

p-Coumaric Acid Nanoparticles Ameliorate Diabetic Nephropathy via Regulating mRNA Expression of KIM-1 and GLUT-2 in Streptozotocin-Induced Diabetic Rats

A Venkatesan, A Roy, S Kulandaivel, V Natesan… - Metabolites, 2022 - mdpi.com
Diabetic nephropathy (DN) has become a leading cause of end-stage renal failure
worldwide. The goal of the current study was to examine the protective effects of chitosan …

Yishen Huashi granules ameliorated the development of diabetic nephropathy by reducing the damage of glomerular filtration barrier

T Zhao, M Li, Q Xiang, B Lie, D Chen… - Frontiers in …, 2022 - frontiersin.org
Background: Diabetic nephropathy (DN) is one of the most common complications of
diabetes and the primary cause of end-stage renal disease. At present, renin–angiotensin …

[HTML][HTML] Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome

T Ding, S Wang, X Zhang, W Zai, J Fan, W Chen… - Phytomedicine, 2018 - Elsevier
Background Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is
acknowledged as an independent risk factor for cardiovascular disease, which underlines …

Molecular mechanisms of curcumin on diabetes‐induced endothelial dysfunctions: Txnip, ICAM‐1, and NOX2 expressions

N Wongeakin, P Bhattarakosol… - BioMed Research …, 2014 - Wiley Online Library
We aim to investigate the effects of curcumin on preventing diabetes‐induced vascular
inflammation in association with its actions on Txnip, ICAM‐1, and NOX2 enzyme …