Increased abundance of Achromobacter xylosoxidans and Bacillus cereus in upper airway transcriptionally active microbiome of COVID-19 mortality patients indicates …

P Devi, R Maurya, P Mehta, U Shamim… - Microbiology …, 2022 - Am Soc Microbiol
The modulators of severe COVID-19 have emerged as the most intriguing features of SARS-
CoV-2 pathogenesis. This is especially true as we are encountering variants of concern …

[HTML][HTML] Characterization of the upper respiratory bacterial microbiome in critically Ill COVID-19 patients

X Bai, A Narayanan, M Skagerberg, R Ceña-Diez… - Biomedicines, 2022 - mdpi.com
The upper respiratory tract (URT) microbiome can contribute to the acquisition and severity
of respiratory viral infections. The described associations between URT microbiota and …

Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 …

J de Castilhos, E Zamir, T Hippchen… - Clinical infectious …, 2022 - academic.oup.com
Background At the entry site of respiratory virus infections, the oropharyngeal microbiome
has been proposed as a major hub integrating viral and host immune signals. Early studies …

Signatures of COVID-19 severity and immune response in the respiratory tract microbiome

C Merenstein, G Liang, SA Whiteside… - MBio, 2021 - Am Soc Microbiol
Viral infection of the respiratory tract can be associated with propagating effects on the
airway microbiome, and microbiome dysbiosis may influence viral disease. Here, we …

[HTML][HTML] Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

L Wang, JB Cao, BB Xia, YJ Li, X Zhang… - … and Targeted Therapy, 2023 - nature.com
The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2)
infected a substantial proportion of Chinese population, and understanding the factors …

[HTML][HTML] Severe COVID-19 is associated with an altered upper respiratory tract microbiome

MH Shilts, C Rosas-Salazar, BA Strickland… - Frontiers in cellular …, 2022 - frontiersin.org
Background The upper respiratory tract (URT) is the portal of entry of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), and SARS-CoV-2 likely interacts with …

[HTML][HTML] Characterization of altered oropharyngeal microbiota in hospitalized patients with mild SARS-CoV-2 infection

YL Shi, MZ He, MZ Han, HY Gui, P Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19) remains a serious emerging global health problem,
and little is known about the role of oropharynx commensal microbes in infection …

[HTML][HTML] Uncover a microbiota signature of upper respiratory tract in patients with SARS-CoV-2+

M Bellato, M Cappellato, F Longhin, C Del Vecchio… - Scientific Reports, 2023 - nature.com
The outbreak of Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, forced us
to face a pandemic with unprecedented social, economic, and public health consequences …

[HTML][HTML] The lower respiratory tract microbiome of critically ill patients with COVID-19

P Gaibani, E Viciani, M Bartoletti, RE Lewis, T Tonetti… - Scientific reports, 2021 - nature.com
COVID-19 infection may predispose to secondary bacterial infection which is associated
with poor clinical outcome especially among critically ill patients. We aimed to characterize …

[HTML][HTML] Longitudinal study across SARS-CoV-2 variants identifies transcriptionally active microbes (TAMs) associated with Delta severity

P Devi, P Kumari, A Yadav, B Tarai, S Budhiraja… - Iscience, 2023 - cell.com
Emergence of new SARS-CoV-2 VOCs jeopardize global vaccine and herd immunity
safeguards. VOCs interactions with host microbiota might affect clinical course and outcome …