Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine
1939. 94 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1788-5. Mosaic loss …

Abstract Danielsson, M. 2021. Mosaic loss of chromosome Y. methods for detection and
consequences for affected leukocytes and men. Digital Comprehensive Summaries of …

Mosaic loss of chromosome Y (mLOY) refers to the condition in male individuals in which a
detectable fraction of cells lose the Y chromosome. Prevalent in haematopoietic cells, this …

We present a brief introduction of loss of Y chromosome (LOY) in blood and describe the
known risk factors for this condition. We then overview the associations between LOY and …

In the current issue of Haematologica, Ouseph et al. 1 pres-ent new results on the relation
between somatic Y chromosome loss and hematologic malignancies. Mosaic loss of …

Recent discoveries have shown that harboring cells without the Y chromosome in the
peripheral blood is associated with increased risk for all-cause mortality and disease such …

Mosaic loss of the Y chromosome (mLOY) is a common somatic mutation in the blood of
elderly men and several studies have found mLOY in blood cells to be associated with an …

On average, men die earlier than women (1). Although differences in environmental,
lifestyle, and exposure factors certainly explain some of the earlier mortality of men, recent …

Studies in recent years have revealed that increasing age is associated with the
accumulation of post-zygotic genetic aberrations in different cell lineages even in the …

This protocol describes the generation of chimeric mice in which the Y chromosome is
deleted from a proportion of blood cells. This model recapitulates the phenomenon of …