A better understanding of the mechanisms that generate and modulate uterine contractility is
needed if progress is to be made in the prevention or treatment of problems in labour …

The appropriate biomechanical function of the uterus is required for the execution of human
reproduction. These functions range from aiding the transport of the embryo to the …

New Findings What is the topic of this review? To provide an overview of the current
understanding of myometrial contractility and give examples of where this has or is close to …

In this review, we give a state‐of‐the‐art account of uterine contractility, focussing on
excitation–contraction (electro‐mechanical) coupling (ECC). This will show how …

Aberrant uterine contractions can lead to preterm birth and other labour complications and
are a significant cause of maternal morbidity and mortality. To investigate the mechanisms …

Changes in Ca2+ signals within the myometrium have important functional consequences,
as they determine contractility. We show that the basic phasic nature of uterine contractions …

If we are to develop new strategies for the treatment and management of preterm and
dysfunctional term labour, it is imperative that we improve current understanding of the …

New Findings What is the topic of this review? I focus on clinical aspects of uterine
physiology, specifically, myometrial contractility. I bring together and contrast findings using …

The function and regulation of the myometrium, especially during pregnancy, labour and
birth are important in reproductive physiology. It is crucial to understand the mechanisms …

Uterine contractions are important in many reproductive functions including the transport of
sperms and embryo, menstruation, pregnancy and parturition. Improper or irregular uterine …