The literature contains conflicting evidence regarding the existence of DNA damage in
spermatozoa from infertile male patients. To examine this phenomenon, we have studied …

Objective: To evaluate two different assays of human sperm DNA integrity, DNA
denaturation (DD) and DNA fragmentation (DF), and to correlate these with standard semen …

BACKGROUND: The integrity of sperm DNA is important for the success of natural or
assisted fertilization, as well as normal development of the embryo, fetus and child. ICSI, by …

Controversy exists over levels of DNA integrity in the sperm of fertile and infertile men. In
addition, the effect of leukocytospermia on sperm DNA in these 2 groups is unclear. We …

OBJECTIVES: To analyze the relationship between DNA damage and standard semen
parameters (SSP) in patients who present for fertility evaluation. Evaluation of male fertility …

OBJECTIVES: To examine the retention of sperm cytoplasmic droplets (CD) and DNA
denaturation (DD) in semen from fertile and infertile men. METHODS: Semen samples were …

Accurate transmission of information coded in the sperm genome is vital to the pre-and post-
natal development of the offspring. Recent advances in reproductive biology have proposed …

Baseline DNA damage in spermatozoa from fertile and infertile men was compared using a
modified alkali single cell gel electrophoresis (comet) assay. Semen from normozoospermic …

Reports indicate an increase in the incidence of DNA fragmentation in male factor infertility
and its role in the outcome of assisted reproductive techniques (ART). However, reports are …

OBJECTIVE: To explore the association between semen parameters and sperm DNA
damage. DESIGN: Cross-sectional. SETTING: Andrology clinic. PATIENT (S): Two hundred …