Preface to the special issue “Psychedelics and Neurochemistry”

CD Nichols, DE Nichols - Journal of Neurochemistry, 2022 - Wiley Online Library
Psychedelics are a relatively recent field of research that had not gained much support half a
century ago, yet it developed into a much acknowledged, highly relevant field that extends to …

SnapShot: psychedelics and serotonin receptor signaling

RH Gumpper, BL Roth - Cell, 2023 - cell.com
Serotonin (5-hydroxytryptamine; 5HT) signaling regulates processes in every major organ
system, but it is most widely known for its role as a neurotransmitter in modulating a plethora …

Psychedelics as transformative therapeutics

BL Roth, RH Gumpper - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
Over the past decade, psychedelic compounds have emerged as potentially transformative
therapeutics for a variety of intractable neuropsychiatric conditions. However, historically …

Psychedelics as an emerging novel intervention in the treatment of substance use disorder: a review

AJ DiVito, RF Leger - Molecular Biology Reports, 2020 - Springer
Classical psychedelics are a group of drugs characterized by their activation of the serotonin-
2A (5-hydroxytryptamine-2A; 5-HT2A) receptor and the unique hallucinogenic and mystical …

Classic psychedelics: past uses, present trends, future possibilities

A Safron, M Johnson - 2022 - osf.io
Here we consider psychedelics with respect to their mechanisms of action, use, and
implications for our understandings of brain and mind. This review is somewhat …

Molecular targets of psychedelic‐induced plasticity

AM Jaster, M de la Fuente Revenga… - Journal of …, 2022 - Wiley Online Library
Psychedelic research across different disciplines and biological levels is growing at a
remarkably fast pace. In the prospect of a psychedelic drug becoming again an approved …

[HTML][HTML] The Key Role of Intracellular 5-HT2A Receptors: A Turning Point in Psychedelic Research?

J Sapienza - Psychoactives, 2023 - mdpi.com
Psychedelics could have revolutionary potential in psychiatry, although, until recently, the
pharmacodynamic properties of such compounds have not seemed to differ much from …

Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics

AM Jaster, J González-Maeso - Molecular psychiatry, 2023 - nature.com
Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

The promises and perils of psychedelic pharmacology for psychiatry

TD McClure-Begley, BL Roth - Nature Reviews Drug Discovery, 2022 - nature.com
Psychedelic drugs including psilocybin, N, N ʹ-dimethyltryptamine (DMT) and lysergic acid
diethylamide (LSD) are undergoing a renaissance as potentially useful drugs for various …

Beyond the 5-HT2A receptor: classic and nonclassic targets in psychedelic drug action

LP Cameron, J Benetatos, V Lewis… - Journal of …, 2023 - Soc Neuroscience
Serotonergic psychedelics, such as psilocybin and LSD, have garnered significant attention
in recent years for their potential therapeutic effects and unique mechanisms of action …