Nanotechnology-based siRNA delivery strategies for treatment of triple negative breast cancer
R Chadar, P Kesharwani - International Journal of Pharmaceutics, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast cancer characterized by
absence of estrogen (ER) receptor, progesterone (PR) receptor, and human epidermal …
absence of estrogen (ER) receptor, progesterone (PR) receptor, and human epidermal …
[HTML][HTML] Bioengineered siRNA-based nanoplatforms targeting molecular signaling pathways for the treatment of triple negative breast cancer: preclinical and clinical …
D Hattab, A Bakhtiar - Pharmaceutics, 2020 - mdpi.com
Triple negative breast cancer (TNBC) is one of the most aggressive types of breast cancer.
Owing to the absenteeism of hormonal receptors expressed at the cancerous breast cells …
Owing to the absenteeism of hormonal receptors expressed at the cancerous breast cells …
[HTML][HTML] siRNA-based nanocarriers for targeted drug delivery to control breast cancer
Breast cancer is a challenging health issue in women and the second-leading cause of
mortality around world. In this review, we addressed beneficial role of siRNA to control …
mortality around world. In this review, we addressed beneficial role of siRNA to control …
Nanocarriers for delivery of siRNA and co-delivery of siRNA and other therapeutic agents
J Zhao, SS Feng - Nanomedicine, 2015 - Taylor & Francis
A major problem in cancer treatment is the multidrug resistance. siRNA inhibitors have great
advantages to solve the problem, if the bottleneck of their delivery could be well addressed …
advantages to solve the problem, if the bottleneck of their delivery could be well addressed …
Nano-drug delivery system: a promising approach against breast cancer
JA Malik, JA Ansari, S Ahmed, A Khan… - Therapeutic …, 2023 - Taylor & Francis
Breast cancer (BC) is among the most frequent malignancies women face around the globe.
Nanotherapeutics are constantly evolving to overcome the limitations of conventional …
Nanotherapeutics are constantly evolving to overcome the limitations of conventional …
Recent advancements in the design of nanodelivery systems of siRNA for cancer therapy
RNA interference (RNAi) has increased the possibility of restoring RNA drug targets for
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …
cancer treatment. Small interfering RNA (siRNA) is a promising therapeutic RNAi tool that …
Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances
Chemotherapeutic agents have certain limitations when it comes to treating cancer, the most
important being severe side effects along with multidrug resistance developed against them …
important being severe side effects along with multidrug resistance developed against them …
[HTML][HTML] Nanomedicine-based delivery strategies for breast cancer treatment and management
Breast cancer is one of the most common types of cancer among women globally. It is
caused by mutations in the estrogen/progesterone receptors and conventional treatment …
caused by mutations in the estrogen/progesterone receptors and conventional treatment …
[HTML][HTML] Nano-formulated siRNA-based therapeutic approaches for cancer therapy
D Jain, SK Prajapati, A Jain, R Singhal - Nano Trends, 2023 - Elsevier
RNAi is a remarkable treatment strategy to knock down gene overexpression in a variety of
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
disorders, including cancers. RNAi processes allow siRNAs to detect and degrade a …
Formulation and in vitro evaluation of a siRNA delivery nanosystem decorated with gH625 peptide for triple negative breast cancer theranosis
SB Djemaa, S David, K Hervé-Aubert, A Falanga… - European Journal of …, 2018 - Elsevier
The development of an efficient small interfering RNA (siRNA) delivery system has held
scientists interest since the discovery of the RNA interference mechanism (RNAi). This …
scientists interest since the discovery of the RNA interference mechanism (RNAi). This …