[HTML][HTML] Effect of Xiaoyaosan on colon morphology and intestinal permeability in rats with chronic unpredictable mild stress

F Ding, J Wu, C Liu, Q Bian, W Qiu, Q Ma, X Li… - Frontiers in …, 2020 - frontiersin.org
Purpose In our present study, a rat depression model induced by 6 weeks of chronic
unpredictable mild stress (CUMS) was established, and we investigated how Xiaoyaosan …

[HTML][HTML] Xiaoyaosan slows cancer progression and ameliorates gut dysbiosis in mice with chronic restraint stress and colorectal cancer xenografts

Z Zhang, S Shao, Y Zhang, R Jia, X Hu, H Liu… - Biomedicine & …, 2020 - Elsevier
Depression is a risk factor for colorectal cancer (CRC) progression. Xiaoyaosan (XYS) is a
traditional Chinese medicine prescription for treating depression. Our present study aimed to …

Chinese medicine formula Kai-Xin-San ameliorates depression-like behaviours in chronic unpredictable mild stressed mice by regulating gut microbiota-inflammation …

C Cao, M Liu, S Qu, R Huang, M Qi, Z Zhu… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Kai-Xin-San (KXS) has been prescribed by TCM
doctors for treating psychiatric diseases with the core symptoms of anhedonia, amnesia, and …

Effects of Zuojin pill on depressive behavior and gastrointestinal function in rats with chronic unpredictable mild stress: Role of the brain–gut axis

T Wang, YF Yan, L Yang, YZ Huang, XH Duan… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Zoujin pill (ZJP), a medication used to treat gastrointestinal
disorders since the 15th Century in China, have been reported to exert anti-depressant …

Anti-depressive effects of Xiaoyaosan, Shugan and Jianpi herbal treatments: Role on the gut microbiome of CUMS rats

X Liu, M Lv, Y Wang, P Qu, S Li, Z Yu, X Qin - Phytomedicine, 2021 - Elsevier
Background Xiaoyaosan (XYS), a classic traditional Chinese medicine (TCM) prescription
that contained eight Chinese herbs, has been used for treating depression for thousands of …

Anti-depressant effects of Xiaoyaosan on rat model of chronic unpredictable mild stress: a plasma metabonomics study based on NMR spectroscopy

XJ Liu, YZ Zhou, ZF Li, J Cui, ZY Li… - Journal of Pharmacy …, 2012 - academic.oup.com
Objectives To investigate the antidepressant effects of Xiaoyaosan (XYS) in a chronic
unpredictable mild stress (CUMS) depression model. Methods The changes in behaviour …

[HTML][HTML] Xiaoyaosan improves depressive-like behavior in rats with chronic immobilization stress through modulation of the gut microbiota

HZ Zhu, YD Liang, QY Ma, WZ Hao, XJ Li… - Biomedicine & …, 2019 - Elsevier
Depression has become the leading cause of disability worldwide and a growing public
health problem in China. In addition, intestinal flora may be associated with depression. This …

Sesamol ameliorates dextran sulfate sodium-induced depression-like and anxiety-like behaviors in colitis mice: The potential involvement of the gut–brain axis

B Xia, X Liu, X Li, Y Wang, D Wang, R Kou, L Zhang… - Food & Function, 2022 - pubs.rsc.org
Inflammatory bowel disease (IBD) is accompanied by some psychiatric disorders, including
anxiety and depression. Sesamol has been reported to alleviate colitis symptoms and …

[HTML][HTML] Chaihu-shugan-san alleviates depression-like behavior in mice exposed to chronic unpredictable stress by altering the gut microbiota and levels of the bile …

C Ma, D Yuan, SJ Renaud, T Zhou, F Yang… - Frontiers in …, 2022 - frontiersin.org
Chaihu-Shugan-San (CSS) is a traditional botanical drug formula often prescribed to treat
depression in oriental countries, but its pharmacotherapeutic mechanism remains unknown …

[HTML][HTML] Tong-Xie-Yao-Fang improves intestinal permeability in diarrhoea-predominant irritable bowel syndrome rats by inhibiting the NF-κB and notch signalling …

Q Hou, Y Huang, Z Zhu, L Liao, X Chen, Q Han… - … and alternative medicine, 2019 - Springer
Abstract Background Tong-Xie-Yao-Fang (TXYF) has been shown to be effective in
diarrhoea-predominant irritable bowel syndrome (IBS-D) patients. However, the underlying …