Innate lymphoid cells and cancer

N Jacquelot, C Seillet, E Vivier, GT Belz - Nature Immunology, 2022 - nature.com
The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

Y Gao, F Souza-Fonseca-Guimaraes, T Bald… - Nature …, 2017 - nature.com
Avoiding destruction by immune cells is a hallmark of cancer, yet how tumors ultimately
evade control by natural killer (NK) cells remains incompletely defined. Using global …

[HTML][HTML] Type 1 innate lymphoid cell biology: lessons learnt from natural killer cells

Y Jiao, ND Huntington, GT Belz, C Seillet - Frontiers in immunology, 2016 - frontiersin.org
Group 1 innate lymphoid cells (ILCs) comprise the natural killer (NK) cells and ILC1s that
reside within peripheral tissues. Several different ILC1 subsets have recently been …

Natural killers or ILC1s? That is the question

C Seillet, L Brossay, E Vivier - Current opinion in immunology, 2021 - Elsevier
Group 1 innate lymphoid cells (ILCs) comprise the natural killer (NK) cells and ILC1s. Both
cells co-exist in peripheral tissues and despite effort to characterize the molecular identity …

[HTML][HTML] Human natural killer cells and other innate lymphoid cells in cancer: Friends or foes?

P Vacca, E Munari, N Tumino, F Moretta, G Pietra… - Immunology …, 2018 - Elsevier
Innate lymphoid cells (ILC) including NK cells (cytotoxic) and the recently identified “helper”
ILC1, ILC2 and ILC3, play an important role in innate defenses against pathogens. Notably …

Innate lymphoid cells and innate-like T cells in cancer—at the crossroads of innate and adaptive immunity

B Ruf, TF Greten, F Korangy - Nature Reviews Cancer, 2023 - nature.com
Immunotherapies targeting conventional T cells have revolutionized systemic treatment for
many cancers, yet only a subset of patients benefit from these approaches. A better …

Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment

UY Moreno-Nieves, JK Tay… - Proceedings of the …, 2021 - National Acad Sciences
Natural killer (NK) cells comprise one subset of the innate lymphoid cell (ILC) family. Despite
reported antitumor functions of NK cells, their tangible contribution to tumor control in …

NK cells and type 1 innate lymphoid cells: partners in host defense

H Spits, JH Bernink, L Lanier - Nature immunology, 2016 - nature.com
Innate lymphoid cells (ILCs) are effectors and regulators of innate immunity and tissue
modeling and repair. Researchers have identified subsets of ILCs with differing functional …

Innate lymphoid cells: a new paradigm in immunology

G Eberl, M Colonna, JP Di Santo, ANJ McKenzie - Science, 2015 - science.org
BACKGROUND Innate lymphoid cells (ILCs) are a growing family of immune cells that mirror
the phenotypes and functions of T cells. Natural killer (NK) cells can be considered the …

Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets

ML Robinette, A Fuchs, VS Cortez, JS Lee, Y Wang… - Nature …, 2015 - nature.com
The recognized diversity of innate lymphoid cells (ILCs) is rapidly expanding. Three ILC
classes have emerged, ILC1, ILC2 and ILC3, with ILC1 and ILC3 including several subsets …