[HTML][HTML] Chronic activation profile of circulating CD8+ T cells in Sézary syndrome

MP Torrealba, KC Manfrere, DR Miyashiro, JF Lima… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Sézary syndrome (SS) is a leukemic variant of cutaneous T cell lymphoma (CTCL), and the
neoplastic CD4+ T cells of SS patients undergo intense clonal proliferation. Although Sézary …

[PDF][PDF] Identification of CD39 as a marker for the circulating malignant T-cell clone of Sézary syndrome patients

A Bensussan, B Janela, N Thonnart, M Bagot… - Journal of Investigative …, 2019 - Elsevier
Sézary syndrome (SS) represents a subtype of cutaneous T-cell lymphoma characterized by
the presence of a malignant CD4+ T-cell clone that accumulates mainly in the skin and …

[HTML][HTML] CD158k is a reliable marker for diagnosis of Sézary syndrome and reveals an unprecedented heterogeneity of circulating malignant cells

H Moins-Teisserenc, M Daubord, E Clave… - Journal of Investigative …, 2015 - Elsevier
The diverse aspects of cutaneous T-cell lymphomas may impede the diagnosis of Sézary
syndrome (SS) and mycosis fungoides (MF), in particular, at early stages of the disease. We …

Sézary Syndrome, recent biomarkers and new drugs

C Cristofoletti, MG Narducci… - Chinese Clinical Oncology, 2019 - cco.amegroups.org
Sézary Syndrome (SS) is a primary cutaneous T-cell lymphoma (CTCL) characterized by
erythroderma, lymphadenopathy and leukemic involvement of the peripheral blood. The …

Absence of CD26 expression on skin‐homing CLA+ CD4+ T lymphocytes in peripheral blood is a highly sensitive marker for early diagnosis and therapeutic …

M Sokolowska‐Wojdylo, J Wenzel… - Clinical and …, 2005 - academic.oup.com
Patients with Sézary syndrome (SS) show clonal expansion in the peripheral blood of skin‐
homing CD4+ T‐helper cells expressing cutaneous lymphocyte antigen (CLA). However, an …

Association of change in clinical status and change in the percentage of the CD4+ CD26− lymphocyte population in patients with Sezary syndrome

CE Introcaso, SD Hess, M Kamoun, R Ubriani… - Journal of the American …, 2005 - Elsevier
BACKGROUND: Because there are currently many effective therapies available for Sézary
syndrome, close monitoring of disease progression is required in order for a clinician to …

Improved Sézary cell detection and novel insights into immunophenotypic and molecular heterogeneity in Sézary syndrome

S Najidh, CP Tensen… - Blood, The Journal …, 2021 - ashpublications.org
Sézary syndrome (SS) is an aggressive leukemic form of cutaneous T-cell lymphoma with
neoplastic CD4+ T cells present in skin, lymph nodes, and blood. Despite advances in …

Genotypic, phenotypic and functional analysis of CD4+CD7+ and CD4+CD7 T lymphocyte subsets in Sézary syndrome

R Dummer, FO Nestle, E Niederer, E Ludwig… - Archives of …, 1999 - Springer
The expansion of CD4+ CD7–T cells in the peripheral blood of Sézary syndrome (SS) is well
known. It remains unclear whether this population contains the dominant T cell clone …

[HTML][HTML] Genetically driven CD39 expression affects sezary cell viability and IL-2 production and detects two patient subsets with distinct prognosis

M Picozza, C Cristofoletti, A Bresin, M Fioretti… - Journal of Investigative …, 2022 - Elsevier
Sezary Syndrome (SS) is a rare and aggressive variant of Cutaneous T-Cell Lymphoma. It is
characterized by the co-presence of CD4+ neoplastic lymphocytes, named Sezary cells …

Single-cell heterogeneity in Sézary syndrome

TB Buus, A Willerslev-Olsen, S Fredholm… - Blood …, 2018 - ashpublications.org
Sézary syndrome (SS) is an aggressive leukemic variant of cutaneous T-cell lymphoma
(CTCL) with a median life expectancy of less than 4 years. Although initial treatment …