[HTML][HTML] Mosaic Chromosomal Alterations Are Associated With Increased Lung Cancer Risk: Insight From the INTEGRAL-ILCCO Cohort Analysis
Introduction Mosaic chromosomal alterations (mCAs) detected in white blood cells represent
a type of clonal hematopoiesis (CH) that is understudied compared with CH-related somatic …
a type of clonal hematopoiesis (CH) that is understudied compared with CH-related somatic …
Interplay between mosaic chromosomal alterations and polygenic risk score increases risk of non-small cell lung cancer
N Qin, C Chen, L Yang, S Liu, Y Xie, X Xu, J Zhou… - medRxiv, 2022 - medrxiv.org
We investigated autosomal mosaic chromosomal alterations (mCAs) in 10,248 non-small
cell lung cancer (NSCLC) cases and 9,298 cancer-free controls of Chinese ancestry. Mosaic …
cell lung cancer (NSCLC) cases and 9,298 cancer-free controls of Chinese ancestry. Mosaic …
Association of the interaction between mosaic chromosomal alterations and polygenic risk score with the risk of lung cancer: an array-based case-control association …
N Qin, C Wang, C Chen, L Yang, S Liu, J Xiang… - The Lancet …, 2022 - thelancet.com
Background Mosaic chromosomal alterations (mCAs) detected from blood-derived DNA are
large structural alterations of clonal haematopoietic origin and are associated with various …
large structural alterations of clonal haematopoietic origin and are associated with various …
INTEGRAL‐ILCCO cohort data analysis revealed the association of clonal haematopoiesis with an increased risk of lung cancer
To investigate the association between clonal haematopoiesis (CH) and lung cancer risk,
we identified CH mutations in 1 059 lung cancer cases and 899 controls using the blood …
we identified CH mutations in 1 059 lung cancer cases and 899 controls using the blood …
Clonal hematopoiesis mutations in patients with lung cancer are associated with lung cancer risk factors
Clonal hematopoiesis (CH) is a phenomenon caused by expansion of white blood cells
descended from a single hematopoietic stem cell. While CH can be associated with …
descended from a single hematopoietic stem cell. While CH can be associated with …
Genetics of smoking and risk of clonal hematopoiesis
Clonal hematopoiesis of indeterminate potential (CHIP) and mosaic chromosomal
alterations (mCAs) represent two forms of clonal hematopoiesis where clones bearing …
alterations (mCAs) represent two forms of clonal hematopoiesis where clones bearing …
[HTML][HTML] Association of mosaic loss of chromosome Y with lung cancer risk and prognosis in a Chinese population
N Qin, N Li, C Wang, Z Pu, Z Ma, G Jin, M Zhu… - Journal of Thoracic …, 2019 - Elsevier
Introduction Mosaic loss of chromosome Y (mLOY) is the most commonly detectable mosaic
chromosomal event in cancers; however, its underlying relationship with tumorigenesis is …
chromosomal event in cancers; however, its underlying relationship with tumorigenesis is …
Clonal hematopoiesis and risk of incident lung cancer
PURPOSE To prospectively examine the association between clonal hematopoiesis (CH)
and subsequent risk of lung cancer. METHODS Among 200,629 UK Biobank (UKBB) …
and subsequent risk of lung cancer. METHODS Among 200,629 UK Biobank (UKBB) …
821P Circulating chromosomal alterations in lymphoid malignancies
R Griffin, NJ Boddicker, EG Franke… - Annals of …, 2024 - annalsofoncology.org
Background Mosaic chromosomal alterations (mCAs) are a promising biomarker for
lymphoid malignancies (LMs). mCAs represent a form of clonal hematopoiesis …
lymphoid malignancies (LMs). mCAs represent a form of clonal hematopoiesis …
Association of clonal hematopoiesis and mosaic chromosomal alterations with solid malignancy incidence and mortality
P Desai, Y Zhou, J Grenet, SK Handelman… - Cancer, 2024 - Wiley Online Library
Background Understanding the impact of clonal hematopoiesis of indeterminate potential
(CHIP) and mosaic chromosomal alterations (mCAs) on solid tumor risk and mortality can …
(CHIP) and mosaic chromosomal alterations (mCAs) on solid tumor risk and mortality can …
相关搜索
- chromosomal alterations clonal hematopoiesis
- chromosomal alterations gene mutations
- chromosomal alterations evolutionary trajectory
- lung cancer increased risk
- lung cancer hematopoiesis mutations
- clonal haematopoiesis increased risk
- lung cancer association of the interaction
- lung cancer clonal haematopoiesis
- lung cancer risk score