Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
The putative neurodegenerative links between depression and Alzheimer's disease
Alzheimer's disease (AD) is the leading neurodegenerative cause of dementia in the elderly.
Thus far, there is no curative treatment for this devastating condition, thereby creating …
Thus far, there is no curative treatment for this devastating condition, thereby creating …
[HTML][HTML] Similarities between depression and neurodegenerative diseases: pathophysiology, challenges in diagnosis and treatment options
Depressive disorder and neurodegenerative diseases are two different clinical entities.
Depression is a common psychiatric disorder in the general population. However, when …
Depression is a common psychiatric disorder in the general population. However, when …
Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …
A common challenge in older adults: Classification, overlap, and therapy of depression and dementia
T Leyhe, CF Reynolds III, T Melcher, C Linnemann… - Alzheimer's & …, 2017 - Elsevier
Late-life depression is frequently associated with cognitive impairment. Depressive
symptoms are often associated with or even precede a dementia syndrome. Moreover …
symptoms are often associated with or even precede a dementia syndrome. Moreover …
Stuck in a rut: rethinking depression and its treatment
PE Holtzheimer, HS Mayberg - Trends in neurosciences, 2011 - cell.com
The current definition of major depressive disorder (MDD) emerged from efforts to create
reliable diagnostic criteria for clinical and research use. However, despite decades of …
reliable diagnostic criteria for clinical and research use. However, despite decades of …
[HTML][HTML] Is dysregulation of the HPA-axis a core pathophysiology mediating co-morbid depression in neurodegenerative diseases?
There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …
[HTML][HTML] Mechanisms underlying neurocognitive dysfunctions in recurrent major depression
P Gałecki, M Talarowska, G Anderson… - … medical journal of …, 2015 - ncbi.nlm.nih.gov
Recent work shows that depression is intimately associated with changes in cognitive
functioning, including memory, attention, verbal fluency, and other aspects of higher-order …
functioning, including memory, attention, verbal fluency, and other aspects of higher-order …
Cognitive dysfunction in depression–pathophysiology and novel targets
AF Carvalho, KK Miskowiak… - CNS & Neurological …, 2014 - ingentaconnect.com
Major depressive disorder (MDD) is associated with cognitive dysfunction encompassing
several domains, including memory, executive function, processing speed and attention …
several domains, including memory, executive function, processing speed and attention …
[HTML][HTML] The pathobiological basis of depression in Parkinson disease: challenges and outlooks
KA Jellinger - Journal of neural transmission, 2022 - Springer
Depression, with an estimated prevalence of about 40% is a most common neuropsychiatric
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …
disorder in Parkinson disease (PD), with a negative impact on quality of life, cognitive …
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