[HTML][HTML] Genetic susceptibility to chronic kidney disease–some more pieces for the heritability puzzle

M Cañadas-Garre, K Anderson, R Cappa… - Frontiers in …, 2019 - frontiersin.org
Chronic kidney disease (CKD) is a major global health problem with an increasing
prevalence partly driven by aging population structure. Both genomic and environmental …

Multiple loci associated with indices of renal function and chronic kidney disease

A Köttgen, NL Glazer, A Dehghan, SJ Hwang, R Katz… - Nature …, 2009 - nature.com
Chronic kidney disease (CKD) has a heritable component and is an important global public
health problem because of its high prevalence and morbidity. We conducted genome-wide …

Chronic kidney disease: novel insights from genome-wide association studies

CA Böger, IM Heid - Kidney and Blood Pressure Research, 2011 - karger.com
Chronic kidney disease (CKD) is common, affecting about 10% of the general population,
and causing significant morbidity and mortality. Apart from the risk conferred by traditional …

Genome-wide association studies in nephrology research

A Köttgen - American Journal of Kidney Diseases, 2010 - Elsevier
Kidney diseases constitute a serious public health burden worldwide, with substantial
associated morbidity and mortality. The role of a genetic contribution to kidney disease is …

Genetic and epigenetic factors influencing chronic kidney disease

LJ Smyth, S Duffy, AP Maxwell… - American Journal of …, 2014 - journals.physiology.org
Chronic kidney disease (CKD) has become a serious public health problem because of its
associated morbidity, premature mortality, and attendant healthcare costs. The rising …

Genome-wide association studies of chronic kidney disease: what have we learned?

CM O'seaghdha, CS Fox - Nature Reviews Nephrology, 2012 - nature.com
The past 3 years have witnessed a dramatic expansion in our knowledge of the genetic
determinants of estimated glomerular filtration rate (eGFR) and chronic kidney disease …

Genome-wide studies to identify risk factors for kidney disease with a focus on patients with diabetes

F Regele, K Jelencsics, D Shiffman… - Nephrology Dialysis …, 2015 - academic.oup.com
Chronic kidney disease (CKD) affects 10–13% of the general population and diabetic
nephropathy (DN) is the leading cause of end-stage renal disease (ESRD). In addition to …

[HTML][HTML] Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) controversies conference

A Köttgen, E Cornec-Le Gall, J Halbritter, K Kiryluk… - Kidney international, 2022 - Elsevier
Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as
well as genes for complex kidney diseases that manifest in combination with environmental …

[HTML][HTML] Genomic approaches in the search for molecular biomarkers in chronic kidney disease

M Cañadas-Garre, K Anderson, J McGoldrick… - Journal of translational …, 2018 - Springer
Background Chronic kidney disease (CKD) is recognised as a global public health problem,
more prevalent in older persons and associated with multiple co-morbidities. Diabetes …

Association between telomere length, chronic kidney disease, and renal traits: a systematic review

OI Ameh, IG Okpechi, C Dandara… - Omics: a journal of …, 2017 - liebertpub.com
Telomere length (TL) is an important biological variable that can influence a variety of
disease-related complex traits as well as host–environment interactions such as drug and …