Multiple Sclerosis (MS) is an immune-mediated neurological disorder, characterized by
central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system
characterized by a complex lesion microenvironment. Although much progress has been …

Multiple sclerosis (MS) is an autoimmune central nervous system (CNS) demyelinating
disease that causes relapsing and chronic neurologic impairment. Recent observations …

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …

In recent years it has become clear that the neuronal compartment already plays an
important role early in the pathology of multiple sclerosis (MS). Neuronal injury in the course …

In contrast to the multiple disease-modifying therapies that are available for relapsing–
remitting multiple sclerosis (MS), the therapeutic options for progressive MS (PMS) are …

Axonal loss in multiple sclerosis (MS) is a key component of disease progression and
permanent neurologic disability. MS is a heterogeneous demyelinating and …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS) characterized by encephalitogenic leukocyte infiltration and …

Although the cause of multiple sclerosis (MS) has remained obscure, many findings support
an autoimmune pathogenesis on the background of a complex interaction between multiple …

The autoimmune model of multiple sclerosis (MS) pathogenesis provided for many years a
useful but incomplete conceptual framework for understanding the complex array of factors …