Using the specific antibodies pLC1 and pLC2 for mono-and diphosphorylated 20-kDa
myosin light chain (MLC20) at Ser19 and at both Thr18 and Ser19, respectively, we …

Phosphorylation of the regulatory light chain of myosin II (MLC20) at the activation sites
promotes both the motor activity and the filament formation of myosin II, thus playing an …

When the rabbit thoracic artery was stimulated with submaximal concentrations of agonist
[40 mM K+, 30 μM prostaglandin F 2α (PGF 2α) or 7 μM histamine], about 90% of a maximal …

The characteristics of actively growing smooth muscle cells (a variant, SM-3) were compared
with those of growth-arrested cells with regard to response of myosin light chain (MLC) …

These experiments were performed to test the hypotheses that myosin light chain 17
(MLC17) a and b isoform expression varies between individual vascular smooth muscle …

Phosphorylation of the regulatory light chain of myosin II (RMLC) at Serine 19 by a specific
enzyme, MLC kinase, is believed to control the contractility of actomyosin in smooth muscle …

The principal signal to activate smooth muscle contraction is phosphorylation of the
regulatory light chains of myosin (LC 20) at Ser 19 by Ca 2+/calmodulin-dependent myosin …

Background In anchorage dependent cells, myosin generated contractile forces affect
events closely associated with adhesion such as the formation of stress fibers and focal …

Nonmuscle myosin II activity is regulated by phosphorylation of the myosin II regulatory light
chain (MRLC) at Ser19 or at both Thr18 and Ser19, and the phosphorylation of MRLC …

Myosin light chain kinase (MLCK) is a regulatory protein for smooth muscle contraction,
which acts by phosphorylating 20‐kDa myosin light chain (MLC20) to activate the myosin …