Cancer management by tyrosine kinase inhibitors: efficacy, limitation, and future strategies
VWT Ho, HY Tan, N Wang, Y Feng - Tyrosine Kinases as …, 2019 - books.google.com
Tyrosine kinase inhibitors are taking up an increasingly significant role in treating cancers.
There are different types of TKIs currently used in clinical settings. However, TKI-associated …
There are different types of TKIs currently used in clinical settings. However, TKI-associated …
More than a decade of tyrosine kinase inhibitors in the treatment of solid tumors: what we have learned and what the future holds
M Vergoulidou - Biomarker insights, 2015 - journals.sagepub.com
The use of tyrosine kinase inhibitors (TKIs) in the treatment of solid tumors is the expected
standard of care for many types of tumors. Since the description of signal transduction …
standard of care for many types of tumors. Since the description of signal transduction …
Protein tyrosine kinase inhibitors in cancer therapy
S Boutayeb, FZ Zakkouri, M Aitelhaj… - Pathologie …, 2012 - europepmc.org
The tyrosine kinase inhibitors (TKI) are small molecules of low molecular weight that inhibit
tyrosine kinases, enzymes responsible for the activation of signal transduction cascades …
tyrosine kinases, enzymes responsible for the activation of signal transduction cascades …
[PDF][PDF] Tyrosine Kinases: promising targets for cancer chemotherapy
VS Kasture, DS Musmade, SJ Aher… - Med Chem Drug Discov, 2012 - academia.edu
Cancer chemotherapy has been one of the major medical advances in the last few decades.
However, the drugs used for this therapy have a narrow therapeutic index, and often the …
However, the drugs used for this therapy have a narrow therapeutic index, and often the …
[HTML][HTML] Tyrosine kinase inhibitors
RJ Thomson, M Moshirfar, Y Ronquillo - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Tyrosine Kinase Inhibitors - StatPearls - NCBI Bookshelf US flag An official website of the
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …
United States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …
Emerging importance of tyrosine kinase inhibitors against cancer: quo vadis to cure?
GLOBOCAN 2020 estimated more than 19.3 million new cases, and about 10 million
patients were deceased from cancer in 2020. Clinical manifestations showed that several …
patients were deceased from cancer in 2020. Clinical manifestations showed that several …
Role of tyrosine kinase inhibitors in cancer therapy
A Arora, EM Scholar - Journal of Pharmacology and Experimental …, 2005 - ASPET
Cancer chemotherapy has been one of the major medical advances in the last few decades.
However, the drugs used for this therapy have a narrow therapeutic index, and often the …
However, the drugs used for this therapy have a narrow therapeutic index, and often the …
Tyrosine kinase inhibitors
Over the last ten years, several new and therapeutically relevant cancer drugs targeting
tyrosine kinase signaling pathways have been developed. Tyrosine kinase inhibitors (TKIs) …
tyrosine kinase signaling pathways have been developed. Tyrosine kinase inhibitors (TKIs) …
A new challenging and promising era of tyrosine kinase inhibitors
JJ Cui - ACS Medicinal Chemistry Letters, 2014 - ACS Publications
Protein kinases are key regulators that govern complex cellular processes. Dysregulation of
kinase signaling is associated in many human diseases, particularly cancers and …
kinase signaling is associated in many human diseases, particularly cancers and …
Small-molecule inhibitors of the receptor tyrosine kinases: promising tools for targeted cancer therapies
M Hojjat-Farsangi - International journal of molecular sciences, 2014 - mdpi.com
Chemotherapeutic and cytotoxic drugs are widely used in the treatment of cancer. In spite of
the improvements in the life quality of patients, their effectiveness is compromised by several …
the improvements in the life quality of patients, their effectiveness is compromised by several …