[HTML][HTML] Tiered testing of micro-and nanoplastics using intestinal in vitro models to support hazard assessments

G Bredeck, B Halamoda-Kenzaoui, A Bogni… - Environment …, 2022 - Elsevier
The uncertainty of potential risks associated with micro-and nanoplastics (MNPs) are of
growing public concern. However, the diversity of MNPs in the environment makes a …

Recent Progress in Intestinal Toxicity of Microplastics and Nanoplastics: Systematic Review of Preclinical Evidence

M Djouina, S Loison, M Body-Malapel - Microplastics, 2024 - mdpi.com
The tremendous plastic production and poor post-use management are current and future
sources of environmental and human contamination due to their degradation products …

Long-term effects of polystyrene nanoplastics in human intestinal Caco-2 cells

J Domenech, M de Britto, A Velázquez, S Pastor… - Biomolecules, 2021 - mdpi.com
The increasing presence of micro-and nanoplastics (MNPLs) in the environment, and their
consequent accumulation in trophic niches, could pose a potential health threat to humans …

Interactions of polystyrene nanoplastics with in vitro models of the human intestinal barrier

J Domenech, A Hernández, L Rubio, R Marcos… - Archives of …, 2020 - Springer
The universal presence of micro-nanoplastics (MNPLs) and its relative unknown effects on
human health is a concern demanding reliable data to evaluate their safety. As ingestion is …

[HTML][HTML] Can the impact of micro-and nanoplastics on human health really be assessed using in vitro models? A review of methodological issues

V Forest, J Pourchez - Environment International, 2023 - Elsevier
Because of the many advantages they offer (strength, low cost, durability, lightweight,
resistance, etc.), plastics are integral part of our daily life with a production constantly rising …

Immunotoxicity and intestinal effects of nano-and microplastics: a review of the literature

N Hirt, M Body-Malapel - Particle and fibre toxicology, 2020 - Springer
Background Together with poor biodegradability and insufficient recycling, the massive
production and use of plastics have led to widespread environmental contamination by nano …

Fate and impact of nanoplastics in the human digestive environment after oral exposure: A common challenge for toxicology and chemistry

C Liebgott, I Chaib, P Doyen, H Robert… - TrAC Trends in …, 2023 - Elsevier
Nanoplastics (NPLs), the presence in the environment of which was considered only “highly
plausible” until recently, have become the focus of environmental and ecotoxicological …

[HTML][HTML] Investigating nanoplastics toxicity using advanced stem cell-based intestinal and lung in vitro models

M Busch, H Brouwer, G Aalderink, G Bredeck… - Frontiers in …, 2023 - frontiersin.org
Plastic particles in the nanometer range–called nanoplastics–are environmental
contaminants with growing public health concern. As plastic particles are present in water …

Nanoplastics as a potential environmental health factor: effects of polystyrene nanoparticles on human intestinal epithelial Caco-2 cells

C Cortés, J Domenech, M Salazar, S Pastor… - Environmental …, 2020 - pubs.rsc.org
The ubiquitous and increasing presence of micro-/nanoplastics (MNPLs) in our environment
demands an urgent hazard assessment, in order to determine the potential risk they pose to …

Potential adverse health effects of ingested micro- and nanoplastics on humans. Lessons learned from in vivo and in vitro mammalian models

L Rubio, R Marcos, A Hernández - Journal of Toxicology and …, 2020 - Taylor & Francis
In recent years, increasing global attention has focused on “microplastics”(MPs) and
“nanoplastics”(NPs) resulting in many studies on the effects of these compounds on …