Non-coding RNA networks in cancer
E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …
Non-coding RNAs, epigenetics, and cancer: tying it all together
HJ Ferreira, M Esteller - Cancer and Metastasis Reviews, 2018 - Springer
While only a small part of the human genome encodes for proteins, biological functions for
the so-called junk genome are increasingly being recognized through high-throughput …
the so-called junk genome are increasingly being recognized through high-throughput …
Large non-coding RNAs: missing links in cancer?
Cellular homeostasis is achieved by the proper balance of regulatory networks that if
disrupted can lead to cellular transformation. These cell circuits are fine-tuned and …
disrupted can lead to cellular transformation. These cell circuits are fine-tuned and …
[HTML][HTML] Noncoding RNA in oncogenesis: a new era of identifying key players
G Deng, G Sui - International journal of molecular sciences, 2013 - mdpi.com
New discoveries and accelerating progresses in the field of noncoding RNAs (ncRNAs)
continuously challenges our deep-rooted doctrines in biology and sometimes our …
continuously challenges our deep-rooted doctrines in biology and sometimes our …
[HTML][HTML] Noncoding RNA: RNA regulatory networks in cancer
JJ Chan, Y Tay - International journal of molecular sciences, 2018 - mdpi.com
Noncoding RNAs (ncRNAs) constitute the majority of the human transcribed genome. This
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …
largest class of RNA transcripts plays diverse roles in a multitude of cellular processes, and …
[HTML][HTML] The role of non-coding RNAs in oncology
FJ Slack, AM Chinnaiyan - Cell, 2019 - cell.com
For decades, research into cancer biology focused on the involvement of protein-coding
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
genes. Only recently was it discovered that an entire class of molecules, termed non-coding …
[HTML][HTML] Non-coding RNAs in cancer initiation and progression and as novel biomarkers
SP Nana-Sinkam, CM Croce - Molecular oncology, 2011 - Elsevier
Cancer represents a complex group of heterogeneous diseases. While many cancers share
fundamental biological processes (hallmarks of cancer) necessary for their development …
fundamental biological processes (hallmarks of cancer) necessary for their development …
[HTML][HTML] Non-coding RNAs: the riddle of the transcriptome and their perspectives in cancer
MA Diamantopoulos, P Tsiakanikas… - Annals of translational …, 2018 - ncbi.nlm.nih.gov
Non-coding RNAs (ncRNAs) constitute a heterogeneous group of RNA molecules in terms
of biogenesis, biological function as well as length and structure. These biological …
of biogenesis, biological function as well as length and structure. These biological …
Non-coding RNAs: the new central dogma of cancer biology
The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …
protein translation. Until the last decade, most researches were geared towards …
Long noncoding RNAs: at the intersection of cancer and chromatin biology
AM Schmitt, HY Chang - Cold Spring …, 2017 - perspectivesinmedicine.cshlp.org
Although only 2% of the genome encodes protein, RNA is transcribed from the majority of
the genetic sequence, suggesting a massive degree of cellular functionality is programmed …
the genetic sequence, suggesting a massive degree of cellular functionality is programmed …