Clonal hematopoiesis of indeterminate potential predicts adverse outcomes in patients with atherosclerotic cardiovascular disease

ED Gumuser, A Schuermans, SMJ Cho… - Journal of the American …, 2023 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP)—the age-related clonal
expansion of blood stem cells with leukemia-associated mutations—is a novel …

Clonal hematopoiesis of indeterminate potential is associated with coronary microvascular dysfunction in early nonobstructive coronary artery disease

N Akhiyat, T Lasho, M Ganji, T Toya… - … , and vascular biology, 2023 - Am Heart Assoc
Background: Clonal hematopoiesis (CH) of indeterminate potential (CHIP) is a risk factor for
cardiovascular disease. The relationship between CHIP and coronary microvascular …

Association of clonal hematopoiesis with incident heart failure

B Yu, MB Roberts, LM Raffield, SM Zekavat… - Journal of the American …, 2021 - jacc.org
Background Age-related clonal hematopoiesis of indeterminate potential (CHIP), defined as
clonally expanded leukemogenic sequence variations (particularly in DNMT3A, TET2 …

Healthy lifestyle and clonal hematopoiesis of indeterminate potential: results from the Women's Health Initiative

B Haring, AP Reiner, J Liu, DK Tobias… - Journal of the …, 2021 - Am Heart Assoc
Background Presence of clonal hematopoiesis of indeterminate potential (CHIP) is
associated with a higher risk of atherosclerotic cardiovascular disease, cancer, and …

Clonal Hematopoiesis: Crossroads of Aging, Cardiovascular Disease, and Cancer: JACC Review Topic of the Week

P Libby, R Sidlow, AE Lin, D Gupta, LW Jones… - Journal of the American …, 2019 - jacc.org
A novel, common, and potent cardiovascular risk factor has recently emerged: clonal
hematopoiesis of indeterminate potential (CHIP). CHIP arises from somatic mutations in …

The clinical challenge of clonal hematopoiesis, a newly recognized cardiovascular risk factor

R Sidlow, AE Lin, D Gupta, KL Bolton… - JAMA …, 2020 - jamanetwork.com
Importance Despite current standards of cardiovascular care, a considerable residual
burden of risk remains in both primary and secondary prevention. Clonal hematopoiesis of …

Cardiovascular disease among patients with AML and CHIP-related mutations

O Calvillo-Argüelles, A Schoffel, JM Capo-Chichi… - Cardio Oncology, 2022 - jacc.org
Background Clonal hematopoiesis of indeterminate potential (CHIP) is a novel
cardiovascular disease (CVD) risk factor in individuals without acute myeloid leukemia …

[HTML][HTML] Clonal hematopoiesis and risk of atherosclerotic cardiovascular disease

S Jaiswal, P Natarajan, AJ Silver… - … England Journal of …, 2017 - Mass Medical Soc
Background Clonal hematopoiesis of indeterminate potential (CHIP), which is defined as the
presence of an expanded somatic blood-cell clone in persons without other hematologic …

Association of diet quality with prevalence of clonal hematopoiesis and adverse cardiovascular events

R Bhattacharya, SM Zekavat, MM Uddin… - JAMA …, 2021 - jamanetwork.com
Importance Clonal hematopoiesis of indeterminate potential (CHIP), the expansion of
somatic leukemogenic variations in hematopoietic stem cells, has been associated with …

Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease

CS Marnell, A Bick, P Natarajan - Journal of molecular and cellular …, 2021 - Elsevier
Clonal hematopoiesis of indeterminate potential (CHIP) is the presence of a clonally
expanded hematopoietic stem cell caused by a leukemogenic mutation in individuals …