Growth response of breast epithelial cells to estrogen is influenced by EGF

P Briand, BK Lundholt, J Skouv… - Molecular and cellular …, 1999 - Elsevier
Estrogen-induced growth stimulation has not previously been demonstrated in estrogen
receptor (ER) cDNA transfected human cell lines in contrast to breast cancer cell lines …

Characterization of a nontumorigenic human breast epithelial cell line stably transfected with the human estrogen receptor (ER) cDNA

BK Lundholt, MW Madsen, AE Lykkesfeldt… - Molecular and cellular …, 1996 - Elsevier
Estrogens play an important role in breast cancer and the effect of estrogen on growth of
breast cancer cells has been extensively studied. However, only little information is …

Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines

AS Levenson, VC Jordan - The Journal of steroid biochemistry and …, 1994 - Elsevier
Estrogen responsiveness of breast tumors can be correlated with the presence or absence
of the estrogen receptor (ER). Breast cancer cells that contain ER are, in general, responsive …

Growth inhibition and growth stimulation by estradiol of estrogen receptor transfected human breast epithelial cell lines involve different pathways

BK Lundholt, P Briand, AE Lykkesfeldt - Breast cancer research and …, 2001 - Springer
Epidermal growth factor (EGF) and estradiol (E2) are important mitogens in breast epithelial
cells, and expression of epidermal growth factor receptor (EGFR) and estrogen receptor …

Regulation of epidermal growth factor-receptor by estrogen and antiestrogen in the human breast cancer cell line MCF-7

Y Berthois, XF Dong, PM Martin - Biochemical and biophysical research …, 1989 - Elsevier
Regulation of breast tumor proliferation depends in a large part on a variety of hormones
and growth factors. In this report we show that estrogen and antiestrogen modulate …

Estrogen inhibits the growth of estrogen receptor-negative, but not estrogen receptor-positive, human mammary epithelial cells expressing a recombinant estrogen …

DA Zajchowski, R Sager, L Webster - Cancer research, 1993 - AACR
Estrogen is essential for the growth of the normal mammary gland and most estrogen
receptor (ER)-positive mammary carcinomas. To better understand the differences between …

The role of estrogen in the regulation of EGFR expression

RI Yarden, MA Wilson, M Barth… - EGF Receptor in Tumor …, 1997 - Springer
In breast cancer, epidermal growth factor receptor (EGFR) expression is inversely correlated
with expression of estrogen receptor (ER)(Fitzpatrick et al. 1984; Sainsbury et al. 1985; …

Characterization of the estrogen receptor transfected MCF10A breast cell line 139B6

MJ Pilat, JK Christman, SC Brooks - Breast cancer research and treatment, 1996 - Springer
There has been increasing evidence which suggests that abnormal expression of the
estrogen receptor (ER) protein in nonmalignant breast tissue may be important in the …

Estrogen suppression of EGFR expression in breast cancer cells: a possible mechanism to modulate growth

RI Yarden, MA Wilson… - Journal of cellular …, 2001 - Wiley Online Library
Epidermal growth factor receptor (EGFR) is a transmembrane receptor whose
overexpression in breast cancer predicts for poor prognosis and is inversely correlated with …

Regulation of estrogen receptor messenger ribonucleic acid and protein levels in human breast cancer cell lines by sex steroid hormones, their antagonists, and …

LD Read, GL Greene… - Molecular …, 1989 - academic.oup.com
Since sex steroid hormones and growth factors are known to modulate the proliferation of
breast tumors, we have studied the effects of estrogen and progestin, their antagonists, and …