Engineered nucleic acids encoding a modified erythropoietin and their expression

JP Schrum, NB Afeyan, GJ Sieczkiewicz… - US Patent …, 2014 - Google Patents
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被引用次数：418 相关文章 所有 4 个版本

Methods of increasing endogenous erythropoietin (EPO)

SJ Klaus, AY Lin, TB Neff, Q Wang, V Guenzler-Pukall… - 2003 - Google Patents
2009-07-20 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
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被引用次数：114 相关文章 所有 3 个版本

Engineered nucleic acids and methods of use thereof

JP Schrum, GJ Sieczkiewicz, K Ejebe… - US Patent …, 2017 - Google Patents
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被引用次数：144 相关文章 所有 4 个版本
[PDF] nature.com

A human expression system based on HEK293 for the stable production of recombinant erythropoietin

CL Chin, JB Goh, H Srinivasan, KI Liu, A Gowher… - Scientific reports, 2019 - nature.com
Mammalian host cell lines are the preferred expression systems for the manufacture of
complex therapeutics and recombinant proteins. However, the most utilized mammalian host …
被引用次数：58 相关文章 所有 7 个版本

Modified polynucleotides for the production of G-CSF

A De Fougerolles, KM Wood, SM Elbashir… - US Patent …, 2014 - Google Patents
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被引用次数：151 相关文章 所有 4 个版本

Recombinant DNA sequences, vectors containing them and method for the use thereof

RH Wilson, CR Bebbington - 1987 - Google Patents
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被引用次数：110 相关文章 所有 3 个版本

Modified polynucleotides encoding citeD4

T Chakraborty, A De Fougerolles - US Patent 9,114,113, 2015 - Google Patents
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被引用次数：139 相关文章 所有 4 个版本

Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders

T Chakraborty, A De Fougerolles - US Patent 9,233,141, 2016 - Google Patents
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被引用次数：129 相关文章 所有 4 个版本

Nuclear reprogramming factor and induced pluripotent stem cells

S Yamanaka, K Takahashi… - US Patent App. 12 …, 2009 - Google Patents
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被引用次数：183 相关文章 所有 2 个版本

Method of producing a protein of interest

A De Fougerolles, SM Elbashir - US Patent App. 13/898,983, 2013 - Google Patents
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被引用次数：88 相关文章 所有 2 个版本