Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …

Astrocytes are an abundant subgroup of cells in the central nervous system (CNS) that play
a critical role in controlling neuronal circuits involved in emotion, learning, and memory. In …

Significant stress exposure and psychiatric depression are associated with morphological,
biochemical, and physiological disturbances of astrocytes in specific brain regions relevant …

Modern society is characterized by the ubiquity of stressors that affect every individual to
different extents. Furthermore, experimental, clinical, and epidemiological data have shown …

Alzheimer disease (AD) is a frequent and devastating neurodegenerative disease in
humans, but still no curative treatment has been developed. Although many explicative …

In the central nervous system (CNS) there are a greater number of glial cells than neurons
(between five and ten times more). Furthermore, they have a greater number of functions …

Background Major depressive disorder is a devastating psychiatric illness that affects
approximately 17% of the population worldwide. Astrocyte dysfunction has been implicated …

A growing body of evidence has demonstrated that astrocytes play a pivotal role in the
normal functioning of the nervous system. This new conceptual framework has set the …

An organism's response to stress requires activation of multiple brain regions. This can have
long‐lasting effects on synaptic transmission and plasticity that likely provide adaptive …

Depressive disorders are complex, multifactorial mental disorders with unknown
neurobiology. Numerous theories aim to explain the pathophysiology. According to the …