The world population is ageing rapidly. As society ages, the incidence of physical limitations
is dramatically increasing, which reduces the quality of life and increases healthcare …

The deterioration of skeletal muscle with advancing age has long been anecdotally
recognized and has been of scientific interest for more than 150 years. Over the past several …

Aging is associated with progressive loss of neuromuscular function that often leads to
progressive disability and loss of independence. The term sarcopenia is now commonly …

As we age, there is an age-related loss in skeletal muscle mass and strength, known as
sarcopenia. Sarcopenia results in a decrease in mobility and independence, as well as an …

Aging is associated with significant decline in neuromuscular function and performance.
Sarcopenia, often defined as age-related loss of muscle mass, strength, and functional …

A substantial loss of muscle mass and strength (sarcopenia), a decreased regenerative
capacity, and a compromised physical performance are hallmarks of aging skeletal muscle …

Skeletal muscle is a highly plastic tissue that remarkably adapts to diverse stimuli including
exercise, injury, disuse, and, as discussed here, aging. Humans achieve peak skeletal …

Advancing adult age is associated with profound changes in body composition, the principal
component of which is a decrease in skeletal muscle mass. This age-related loss in skeletal …

Changing demographics make it ever more important to understand the modifiable risk
factors for disability and loss of independence with advancing age. For more than two …

An age-associated loss of muscle mass and strength--sarcopenia--begins at around the fifth
decade of life, with mass being lost at~ 0.5-1.2% per year and strength at~ 3% per year …