[HTML][HTML] Antidepressant and anxiolytic potential of Citrus reticulata Blanco essential oil: a network pharmacology and animal model study

NP Khanh Nguyen, JH Kwon, MK Kim… - Frontiers in …, 2024 - frontiersin.org
Background: Citrus reticulata Blanco essential oil (CBEO) has attracted increasing attention
as a potential treatment for depression and anxiety in recent years. However, there is limited …

Mechanism of lemon essential oil in mitigation of anxiety based on network pharmacology and experimental validation

Z Yi-ping, XU Xu, LYU Yi-ting, H Jin-qin… - NATURAL PRODUCT …, 2024 - trcw.ac.cn
The mechanism of lemon essential oil (LEO) intervention in anxiety disorder was
investigated using network pharmacology, and its efficacy was validated through …

[HTML][HTML] In Silico Prediction of the Anti-Depression Mechanism of a Herbal Formula (Tiansi Liquid) Containing Morinda officinalis and Cuscuta chinensis

D Cheng, G Murtaza, S Ma, L Li, X Li, F Tian, J Zheng… - Molecules, 2017 - mdpi.com
Purpose: Depression is a sickening psychiatric condition that is prevalent worldwide. To
manage depression, the underlying modes of antidepressant effect of herbals are important …

Antidepressant-Like Effect of Essential Oils From Citrus reticulata in Reserpine-Induced Depressive Mouse

M Tang, Y Ai, S Zhu, N Song, X Xu… - Natural Product …, 2022 - journals.sagepub.com
Citrus reticulata Blanco has been widely used to cure some diseases such as cold, cough
and indigestion. This study is aimed at determining the antidepressant-like effect of C …

An integrative metabolomics and network pharmacology method for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba on anti …

H Zhang, S Zhang, M Hu, Y Chen, W Wang… - … of pharmaceutical and …, 2020 - Elsevier
Depression is a common mental illness, which is caused by 'liver qi stagnationin in
traditional Chinese medicine (TCM) theory. Thus, relieving “liver qi stagnation” is considered …

Integrated analysis of phytochemical composition, pharmacokinetics, and network pharmacology to probe distinctions between the stems of Cistanche deserticola and …

L Fan, Y Peng, X Chen, P Ma, X Li - Food & Function, 2022 - pubs.rsc.org
Cistanches Herba (CH), as a nutritional and functional supplement used in food and health
care products for centuries, consists of the stems of Cistanche deserticola and C. tubulosa …

Deciphering the antidepressant effects of Rosa damascena essential oil mediated through the serotonergic synapse signaling pathway

N Xia, J Wang, Q Guo, J Duan, X Wang, P Zhou… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Rosa damascena is an ancient plant with significance in
both medicine and perfumery that have a variety of therapeutic properties, including …

Identification of potential biomarkers of depression and network pharmacology approach to investigate the mechanism of key genes and therapeutic traditional …

Y Shi, D Chen, S Ma, H Xu… - … Based Complementary and …, 2021 - Wiley Online Library
Background. To explore the potential target of depression and the mechanism of related
traditional Chinese medicine in the treatment of depression. Method. Differential gene …

Antidepressant-like Effect of Citrus sinensis (L.) Osbeck Essential Oil and Its Main Component Limonene on Mice

LL Zhang, ZY Yang, G Fan, JN Ren… - Journal of agricultural …, 2019 - ACS Publications
The present study investigated the antidepressant-like effects of navel orange [Citrus
sinensis (L.) Osbeck] essential oil (OEO) and its main components using the chronic …

[HTML][HTML] Antidepressant mechanisms of natural products based on multi-omics technologies

Y Fang, T Zhou - Frontiers in Pharmacology, 2023 - frontiersin.org
Depression has become currently one of the leading causes of disease burden in the world
leading to suicide and ischemic heart disease. Current antidepressant drugs are not …